IgD Inhibitors
IgD inhibitors belong to a specialized chemical class primarily known for their role in modulating the immune system and targeting a specific type of immunoglobulin called IgD. These inhibitors are designed to interfere with the function of IgD, a class of antibodies that plays a unique and somewhat enigmatic role in the immune response. IgD antibodies are less understood compared to their more well-known counterparts, such as IgG or IgM. Unlike other immunoglobulins, IgD is typically found in low concentrations in the bloodstream, making its role in immune function less clear. However, it is primarily associated with B cells, where it is thought to play a crucial role in B cell activation and maturation.
The inhibitors designed to target IgD function are developed to modulate specific immune responses, but their exact mechanisms of action are still under investigation. By interfering with IgD, researchers aim to gain a better understanding of its role in the immune system and its potential implications for immune regulation. IgD inhibitors may have applications in research settings where a deeper understanding of immune responses is needed. These inhibitors serve as valuable tools for scientists exploring the intricacies of the immune system.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate is a dihydrofolate reductase inhibitor that can interfere with the proliferation of B cells that express immunoglobulin D (IgD) by inhibiting folate-dependent processes essential for cell division. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that can modulate the signaling pathways of B cells, potentially influencing the expression or function of IgD by altering the cellular oxidative state and kinase activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate the NF-κB pathway, which is involved in the transcription of many immune-related genes, including those for immunoglobulins like IgD, thus affecting its expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can raise the pH of endosomes, which may impact the processing and presentation of antigens bound to IgD on B cells, thereby influencing IgD-mediated immune responses. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $50.00 $374.00 $2071.00 | 18 | |
Lenalidomide affects the homeostasis of the immune system and can influence the function of B cells, potentially altering IgD dynamics indirectly through immune modulation mechanisms. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
Ibrutinib is a Bruton's tyrosine kinase inhibitor, which can impair B cell receptor signaling, potentially reducing the activity and function of B cells expressing IgD. | ||||||
CAL-101 | 870281-82-6 | sc-364453 | 10 mg | $193.00 | 4 | |
Idelalisib inhibits phosphoinositide 3-kinase delta, which plays a role in B cell receptor signaling, possibly affecting IgD-expressing B cell function. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib is a tyrosine kinase inhibitor that can inhibit multiple kinases involved in B cell signaling, potentially altering the signaling cascade that affects IgD expression or function. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib targets multiple kinases and can disrupt signaling cascades in B cells, which may impact IgD expression or function by altering cellular signaling pathways. | ||||||
R788 | 901119-35-5 | sc-364597 sc-364597A | 2 mg 50 mg | $405.00 $4000.00 | 2 | |
Fostamatinib inhibits spleen tyrosine kinase, an enzyme involved in B cell receptor signaling, and could affect IgD-expressing B cells by modulating their signaling pathways. | ||||||