Date published: 2025-9-9

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Anticorps IDO (E-7): sc-365086

5.0(2)
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Fiches techniques
  • L'Anticorps IDO (E-7) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés . près de N-terminus de IDO d'origine mouse
  • recommandé pour la détection de IDO d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Voir IDO (mIDO-48): sc-53978 pour d'autres anticorps conjugués IDO, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour IDO Antibody (E-7) for WB applications. Ces réactifs sont désormais proposés en lots avec IDO Antibody (E-7)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Indoleamine 2,3-dioxygenase (IDO) is an IFN-γ inducible enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. The gene encoding human IDO maps to chromosome 8p12-p11. IDO, also known as INDO, is an important modulator of immunological responses and protects allogeneic concepti from alloreactive maternal lymphocytes. IDO mediates an interesting inhibitory effect of HeLa cells co-cultured with human PBLs. The ILN-2-induced proliferation response of PBLs is diminished in the presence of HeLa cells while an IDO inhbitor negates this effect. Flow cytometric analysis indicates both mature and immature CD123-positive dentritic cells suppress T cell activity using IDO. IDO-transfected cells co-cultured with T cells reduces T cell proliferation. Additionally, adopted transfer of donor T cells reduces donor T cell numbers in IDO-transgenic mice. The pharmacological or genetic manipulation of IDO may be useful for supressing undesirable T cell response.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps IDO (E-7)

sc-365086
200 µg/ml
$316.00

IDO (E-7): m-IgG Fc BP-HRP Kit

sc-540307
200 µg Ab; 10 µg BP
$354.00

IDO (E-7): m-IgG1 BP-HRP Kit

sc-542029
200 µg Ab; 20 µg BP
$354.00

IDO (E-7) peptide neutralisant

sc-365086 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-365086 P appropriate for?

Posée par: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-02-24
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Rated 5 de 5 de par It works well!I have published 2 papers with this one. It works!!!
Date de publication: 2021-05-01
Rated 5 de 5 de par Produced positive Western blot data of IDOProduced positive Western blot data of IDO expression in non-transfected and mouse IDO transfected 293T whole cell lysates. -SCBT QC
Date de publication: 2014-02-26
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Anticorps IDO (E-7) est évalué 5.0 de 5 de 2.
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