Anticorps Id1 (G-7): sc-374287
- L'Anticorps Id1 (G-7) est un monoclonal de souris IgG1 κ, cité dans 5 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 1-148 correspondant à la séquence totale de Id1 d'origine mouse
- recommandé pour la détection de Id1, Id2, Id3 and Id4 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Voir Id1 (B-8): sc-133104 pour d'autres anticorps conjugués Id1, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps Id1 (G-7) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps Id1 (G-7)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1, Id2, Id3 and Id4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since Id1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the Id protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of each of the Id proteins is strongly dependent on growth factor activation and that reduction of Id mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Id1 (G-7) | sc-374287 | 200 µg/ml | $316.00 | |||
Id1 (G-7): m-IgG Fc BP-HRP Kit | sc-537948 | 200 µg Ab; 10 µg BP | $354.00 | |||
Id1 (G-7): m-IgGκ BP-HRP Kit | sc-535436 | 200 µg Ab; 40 µg BP | $354.00 | |||
Id1 (G-7): m-IgG1 BP-HRP Kit | sc-545464 | 200 µg Ab; 20 µg BP | $354.00 |