Date published: 2025-9-7

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Anticorps Huntingtin (3H2242): sc-71287

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Fiches techniques
  • L'Anticorps Huntingtin (3H2242) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 997-1276 de Huntingtin d'origine mouse
  • recommandé pour la détection de an epitope corresponding to the HDA region (amino acids 1171-1177) of Huntingtin d'origine mouse, rat et human par WB, IP et IF
  • Le m-IgG Fc BP-HRP est le réactif de détection secondaire préféré pour l'anticorps Huntingtin (3H2242) pour les applications WB. Ce réactif est désormais proposé en bundle avec l'anticorps Huntingtin (3H2242)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Huntingtin is a protein that contains a polyglutamine region. When the number of glutamine repeats exceeds 35, the gene encodes a version of Huntingtin that leads to Huntington's disease (HD). When the polyglutamine stretch is mutated, Huntingtin acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. Loss of Huntingtin activity is unlikely to be the cause of HD, and it has been proposed that the expanded glutamine repeat region may induce an abnormal interaction between the mutant protein and other cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), and HIP1.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps Huntingtin (3H2242)

    sc-71287
    200 µg/ml
    $316.00

    Huntingtin (3H2242): m-IgG Fc BP-HRP Kit

    sc-539358
    200 µg Ab; 10 µg BP
    $354.00

    How much sample do you recommend loading on the gel for Western blot detection using Huntingtin (3H2242): sc-71287?

    Posée par: Randy McDonald
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 4 de 5 de par Positive results in western blot with JurkatPositive results in western blot with Jurkat whole cell lysate. -SCBT QC
    Date de publication: 2013-04-14
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    Anticorps Huntingtin (3H2242) est évalué 4.0 de 5 de 1.
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