ACCÈS RAPIDE AUX LIENS
RNA polymerase II transcripts are complexed with hnRNP (heterogeneous nuclear ribonucleoprotein) proteins, which are involved in several aspects of hnRNA maturation and transport. The hnRNP particle U (also designated SP120 and SAF-A for scaffold attachment factor) is an abundant nucleoplasmic phosphoprotein and the largest of the major hnRNP proteins. hnRNP U is specifically involved in pre-mRNA processing and is directly bound to both RNA and DNA. Specifically, hnRNP U has a high affinity to the SAR (scaffold attachment region) of DNA. hnRNP U also functions as an RNA polymerase elongation inhibitor by inhibiting TFIIH-mediated phosphorylation of the carboxy-terminal domain of Pol II. Identical to GRIP120, hnRNP U also associates with glucocorticoid receptors to inhibit glucocorticoid induction.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps hnRNP U (D-2) | sc-365852 | 200 µg/ml | $316.00 | |||
hnRNP U (D-2): m-IgG Fc BP-HRP Kit | sc-540377 | 200 µg Ab; 10 µg BP | $354.00 | |||
hnRNP U (D-2): m-IgG1 BP-HRP Kit | sc-542081 | 200 µg Ab; 20 µg BP | $354.00 |