ACCÈS RAPIDE AUX LIENS
HELIC2, also known as SNRNP200 (small nuclear ribonucleoprotein 200kDa (U5)), ASCC3L1 or BRR2, is a 2,136 amino acid protein that localizes to the nucleus and contains two SEC63 domains, two helicase C-terminal domains and two helicase ATP-binding domains. Existing as multiple alternatively spliced isoforms, HELIC2 functions as an RNA helicase that is thought to promote specific RNA-RNA conformational changes which are important in the second step of RNA splicing. The gene encoding HELIC2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HELIC2 (B-11) | sc-393517 | 200 µg/ml | $316.00 | |||
HELIC2 (B-11): m-IgGκ BP-HRP Kit | sc-535807 | 200 µg Ab; 40 µg BP | $354.00 | |||
HELIC2 (B-11): m-IgG2b BP-HRP Kit | sc-549480 | 200 µg Ab; 10 µg BP | $354.00 |