



ACCÈS RAPIDE AUX LIENS
HELIC2, also known as SNRNP200 (small nuclear ribonucleoprotein 200kDa (U5)), ASCC3L1 or BRR2, is a 2,136 amino acid protein that localizes to the nucleus and contains two SEC63 domains, two helicase C-terminal domains and two helicase ATP-binding domains. Existing as multiple alternatively spliced isoforms, HELIC2 functions as an RNA helicase that is thought to promote specific RNA-RNA conformational changes which are important in the second step of RNA splicing. The gene encoding HELIC2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HELIC2 (B-11) | sc-393517 | 200 µg/ml | $316.00 | |||
HELIC2 (B-11): m-IgGκ BP-HRP Kit | sc-535807 | 200 µg Ab; 40 µg BP | $354.00 | |||
HELIC2 (B-11): m-IgG2b BP-HRP Kit | sc-549480 | 200 µg Ab; 10 µg BP | $354.00 |