Anticorps Histone Deacetylase 4 (HDAC4) (F-6): sc-365367
- L'Anticorps Histone Deacetylase 4 (HDAC4) (F-6) est un monoclonal de souris IgG2a κ, cité dans 2 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 2-23 au niveau N-terminus de HDAC4 d'origine human
- recommandé pour la détection de HDAC4 d'origine mouse, rat, human et par WB, IP, IF et ELISA
- Voir Histone Deacetylase 4 (A-4): sc-46672 pour d'autres anticorps conjugués Histone Deacetylase 4 (HDAC4), dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- 2a BP-HRP">m-IgG2a BP-HRP est le réactif de détection secondaire préféré pour l'anticorps Histone Deacetylase 4 (HDAC4) (F-6) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps Histone Deacetylase 4 (HDAC4) (F-6)(voir les informations relatives à la commande ci-dessous).
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, p300/CBP, PCAF (p300/CBP associated factor), HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Histone Deacetylase 4 (HDAC4) (F-6) | sc-365367 | 200 µg/ml | $316.00 | |||
Histone Deacetylase 4 (HDAC4) (F-6): m-IgG2a BP-HRP Kit | sc-546041 | 200 µg Ab; 10 µg BP | $354.00 | |||
Histone Deacetylase 4 (HDAC4) (F-6) peptide neutralisant | sc-365367 P | 100 µg/0.5 ml | $68.00 |