ACCÈS RAPIDE AUX LIENS
In the central nervous system (CNS), glycine-mediated inhibitory neurotransmission is essential to voluntary motor control and reflex responses. Glycine binds to glycine receptors (GlyR) in the postsynaptic neuronal membranes. GlyR, γ-aminobutryic acid, serotonin and acetylcholine comprise an evolutionally conserved superfamily of ligand-gated ion channels. The pentameric subunit structure of GlyR consists of two types of glycosylated membrane proteins, α1 through α4 and β, and an associated peripheral membrane protein, which combine to form a chloride-selective ion channel. In humans, the composition of the pentamer changes from α2 subunits in the fetal CNS to α1 and β subunits in the adult CNS. Fast potentiation of GlyR by intracellular Ca2+ in the brainstem and midbrain indicate an important role for Ca2+ in modulation of glycinergic synapses.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GlyR β (G-1) | sc-390156 | 200 µg/ml | $316.00 | |||
GlyR β (G-1): m-IgG Fc BP-HRP Kit | sc-538062 | 200 µg Ab; 10 µg BP | $354.00 | |||
GlyR β (G-1): m-IgGκ BP-HRP Kit | sc-535590 | 200 µg Ab; 40 µg BP | $354.00 | |||
GlyR β (G-1): m-IgG1 BP-HRP Kit | sc-545506 | 200 µg Ab; 20 µg BP | $354.00 |