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glypican-3 Antibody (F-3) is an IgM κ mouse monoclonal glypican-3 antibody (also designated GPC3 antibody, or glypican 3 antibody) that detects the glypican-3 protein of mouse, rat and human origin by WB, IP, IF and ELISA. glypican-3 Antibody (F-3) is available as both the non-conjugated anti-glypican-3 antibody form, as well as multiple conjugated forms of anti-glypican-3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Glypican-3 (GPC3) is an integral membrane protein that is mutated in the Simpson-Golabi-Behmel syndrome (SGBS). SGBS is characterized by pre- and post-natal overgrowth and is a recessive X-linked condition. Glypican-3, also designated OCI-5 in rat, is a member of the glypican family of heparan sulfate proteoglycans, which attach to the cell membrane via a glycosyl-phosphatidyl-inositol (GPI) anchor. Expression of glypican-3 is detected in embryonic mesodermal lung, liver and kidney tissues. Glypican-3 is thought to regulate tissue and organ growth through interactions with growth factors such as insulin-like growth factor II (IGF-II) or fibroblast growth factor 2 (FGF-2). Glypican-3 may be downregulated by various means, including promoter hypermethylation or the repression of specific transcription factors.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
LI-COR® et Odyssey® sont marques déposées de LI-COR Biosciences
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps glypican-3 (F-3) | sc-390587 | 200 µg/ml | $316.00 | |||
Anticorps glypican-3 (F-3) AC | sc-390587 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Anticorps glypican-3 (F-3) Alexa Fluor® 488 | sc-390587 AF488 | 200 µg/ml | $357.00 | |||
Anticorps glypican-3 (F-3) Alexa Fluor® 647 | sc-390587 AF647 | 200 µg/ml | $357.00 | |||
Anticorps glypican-3 (F-3) FITC | sc-390587 FITC | 200 µg/ml | $330.00 | |||
Anticorps glypican-3 (F-3) HRP | sc-390587 HRP | 200 µg/ml | $316.00 | |||
glypican-3 (F-3) peptide neutralisant | sc-390587 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps glypican-3 (F-3) PE | sc-390587 PE | 200 µg/ml | $343.00 |