Anticorps GCAP2 (B-8): sc-271107
- L'Anticorps GCAP2 (B-8) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 130-200 correspondant à C-terminus de GCAP2 d'origine human.
- recommandé pour la détection de GCAP2 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps GCAP2 (B-8) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps GCAP2 (B-8) (voir Informations pour la commande ci-dessous).
The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of cGMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event. The genes which encode GCAP1 and GCAP2 map to human chromosome 6p21.1.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GCAP2 (B-8) | sc-271107 | 200 µg/ml | $316.00 | |||
GCAP2 (B-8): m-IgG Fc BP-HRP Kit | sc-537570 | 200 µg Ab; 10 µg BP | $354.00 | |||
GCAP2 (B-8): m-IgGκ BP-HRP Kit | sc-534871 | 200 µg Ab; 40 µg BP | $354.00 | |||
GCAP2 (B-8): m-IgG2a BP-HRP Kit | sc-548055 | 200 µg Ab; 10 µg BP | $354.00 |