Anticorps GCAP2 (6D433): sc-71137
- L'Anticorps GCAP2 (6D433) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- élevé contre le GCAP2 d'origine bovine de pleine longueur
- recommandé pour la détection de GCAP2 d'originie bovine par WB; non cross-reactif avec other isotypes
- m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour GCAP2 Antibody (6D433) pour les applications WB. Ces réactifs sont désormais proposés en lots avec GCAP2 Antibody (6D433)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of cGMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event. The genes which encode GCAP1 and GCAP2 map to human chromosome 6p21.1.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GCAP2 (6D433) | sc-71137 | 200 µg/ml | $316.00 | |||
GCAP2 (6D433): m-IgG Fc BP-HRP Kit | sc-539350 | 200 µg Ab; 10 µg BP | $354.00 | |||
GCAP2 (6D433): m-IgG2a BP-HRP Kit | sc-546694 | 200 µg Ab; 10 µg BP | $354.00 |