DOM3Z Antibody (B-12): sc-393141

DOM3Z Antibody (B-12) is a mouse monoclonal IgG2a antibody that detects DOM3Z in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid protein that is ubiquitously expressed and belongs to the DOM3Z family. Anti-DOM3Z antibody (B-12) plays a crucial role in studying cellular processes, particularly in the regulation of RNA metabolism and the assembly of ribonucleoprotein complexes, which are essential for proper gene expression and cellular function. DOM3Z′s importance in these processes is underscored by its involvement in various diseases; for instance, alterations in DOM3Z expression have been linked to cancer susceptibility, as evidenced by the association of chromosome 6 deletions with early onset intestinal cancer. Furthermore, the gene encoding DOM3Z is located in the major histocompatibility complex (MHC) class III region of chromosome 6, a genomic area that is critical for immune response and has been implicated in several other conditions, including Porphyria cutanea tarda and Parkinson′s disease. DOM3Z monoclonal antibody (B-12)′s versatility in multiple applications makes DOM3Z (B-12) antibody an invaluable tool for researchers studying the functional implications of this important protein in health and disease.

The preferred DOM3Z antibody is DOM3Z Antibody (D-9): sc-393167.