Date published: 2025-9-9

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Anticorps Dim1 (B-9): sc-390839

5.0(1)
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Fiches techniques
  • L'Anticorps Dim1 (B-9) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-142 correspondant à la séquence totale de Dim1 d'origine human
  • recommandé pour la détection de Dim1 d'origine mouse, rat, human et avian par WB, IP, IF et ELISA; également réactif avec d'autres espèces, dont et equine, canine, bovine, porcine and avian
  • Le m-IgG Fc BP-HRP est le réactif de détection secondaire préféré pour l'anticorps Dim1 (B-9) pour les applications WB. Ce réactif est désormais proposé en bundle avec l'anticorps Dim1 (B-9)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The Dim protein family consists of two classes, Dim1 and Dim2, which share a common thioredoxin-like fold, but most likely function in different biological pathways. Dim1, also known as TXNL4A (Thioredoxin-like protein 4A) or Spliceosomal U5 snRNP-specific 15 kDa protein, is a 142 amino acid protein that plays an essential role in pre-mRNA splicing. Due to a failure to express early zygotic transcripts, deletion of the gene encoding Dim1 in Schizosaccharomyces pombe leads to embryonal lethality during gastrulation. Since Dim1 shows sensitivity to a microtubule destabilizing drug, thiabendazole, it also may play a role in the formation of the mitotic spindle. This evidence demonstrates that Dim1 is essential for G2/M progression of the cell cycle and chromosomal segregation during mitosis. Localized to the nucleus, Dim1 interacts with hnRNP F, hnRNP H2, Cas-L and PQBP-1 to effect gene expression.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps Dim1 (B-9)

    sc-390839
    200 µg/ml
    $316.00

    Dim1 (B-9): m-IgG Fc BP-HRP Kit

    sc-540864
    200 µg Ab; 10 µg BP
    $354.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with Dim1 (B-9): sc-390839 monoclonal antibody?

    Posée par: Professor Griffin
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Répondue par: Technical Support
    Date de publication: 2017-02-27
    • y_2025, m_9, d_5, h_6CST
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    Rated 5 de 5 de par Produced positive Western blot data of Dim1Produced positive Western blot data of Dim1 expression in Hep G2 nuclear extract. -SCBT QC
    Date de publication: 2014-09-24
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    Anticorps Dim1 (B-9) est évalué 5.0 de 5 de 1.
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