Date published: 2025-9-10

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Anticorps CSN7a (H-2): sc-514067

5.0(1)
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Fiches techniques
  • L'Anticorps CSN7a (H-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 72-112 dans une région interne de CSN7a d'origine human
  • recommandé pour la détection de CSN7a d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps CSN7a (H-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps CSN7a (H-2)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, IκBα and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system. CSN7 is phosphorylated by CK2 and is composed of two subunits; a and b. CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, as well as a coiled-coil region and is predicted to interact with CSN2, CSN3, CSN4, CSN5, CSN6, CSN8, and GPS1. CSN7b contains only a PCI region and is predicted to interact with INT6.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps CSN7a (H-2)

    sc-514067
    200 µg/ml
    $316.00

    CSN7a (H-2): m-IgG Fc BP-HRP Kit

    sc-538578
    200 µg Ab; 10 µg BP
    $354.00

    CSN7a (H-2): m-IgGκ BP-HRP Kit

    sc-536216
    200 µg Ab; 40 µg BP
    $354.00

    CSN7a (H-2): m-IgG1 BP-HRP Kit

    sc-545778
    200 µg Ab; 20 µg BP
    $354.00

    I need to use an antibody to detect the protein in samples of porcine origin. Do you know if CSN7a (H-2): sc-514067 mouse monoclonal antibody will work?

    Posée par: cjMara
    Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_8, d_31, h_8CST
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    • QUESTIONS, PRODUCT
    Rated 5 de 5 de par Great Western blot data of CSN7a expressionGreat Western blot data of CSN7a expression in HeLa and JAR whole cell lysates, SK-N-MC nuclear extract and human lateral ventricle and human heart tissue extracts. -SCBT QC
    Date de publication: 2013-06-05
    • y_2025, m_8, d_31, h_8
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    Anticorps CSN7a (H-2) est évalué 5.0 de 5 de 1.
    • y_2025, m_8, d_31, h_8
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    • cp_1, bvpage1
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    • CLOUD, getAggregateRating, 125ms
    • REVIEWS, PRODUCT