Anticorps CARD 9 (F-4): sc-365545
- L'Anticorps CARD 9 (F-4) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 98-187 correspondant à une région interne de CARD 9 d'origine human.
- recommandé pour la détection de CARD 9 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour CARD 9 Antibody (F-4) pour les applications WB. Ces réactifs sont désormais proposés en lots avec CARD 9 Antibody (F-4)(voir les informations de commande ci-dessous).
Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3), and the caspase-associated recruitment domain (CARD) proteins: CARD 6, CARD 8-12 and CARD 14. CARD 9 is the main transducer of Dectin-1 signals that consist of mediated myeloid cell activation, cytokine production, and innate anti-fungal immunity. Dectin-1 is the main mammalian receptor that recognizes the fungal component zymosan. CARD 9 self-associates and has coiled-coil motifs that may function as oligomerization domains. Bcl10 interacts with CARD 9 and regulates the zymosan induced NFκB activation. Overexpression of CARD 9 correlates with the development of gastric B-cell lymphoma.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CARD 9 (F-4) | sc-365545 | 200 µg/ml | $316.00 | |||
CARD 9 (F-4): m-IgG Fc BP-HRP Kit | sc-540348 | 200 µg Ab; 10 µg BP | $354.00 | |||
CARD 9 (F-4): m-IgG2a BP-HRP Kit | sc-546895 | 200 µg Ab; 10 µg BP | $354.00 |