Date published: 2025-11-24

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Inhibiteurs DDX26B

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

VOIR ÉGALEMENT...

Nom du produitCAS #Ref. CatalogueQuantitéPrix HTCITATIONS Classement

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

L'actinomycine D se lie à l'ADN, inhibe la transcription et empêche la synthèse de l'ARNm DDX26B.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Le cycloheximide perturbe la synthèse des protéines, ce qui entraîne une réduction de l'expression de DDX26B en inhibant la traduction.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

La puromycine induit une interruption prématurée de la synthèse des protéines, ce qui a un impact sur la traduction et réduit les niveaux de DDX26B.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

La rifampicine inhibe l'ARN polymérase bactérienne, supprimant indirectement l'expression de DDX26B en interférant avec la transcription.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

L'anisomycine entrave la synthèse des protéines en bloquant l'activité de la peptidyl transférase, ce qui entraîne une réduction de la synthèse de DDX26B.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

La cordycépine interfère avec la synthèse de l'ARNm, ce qui a un impact sur la transcription et contribue à la régulation à la baisse de DDX26B.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

L'acide mycophénolique inhibe l'inosine monophosphate déshydrogénase, affectant indirectement l'expression de DDX26B en perturbant la synthèse des purines.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$360.00
$475.00
20
(2)

La blasticidine S induit une terminaison prématurée de la traduction, inhibant la synthèse des protéines et réduisant les niveaux de DDX26B.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

Le 5-fluorouracile interfère avec la synthèse de l'ARN, affectant l'expression de DDX26B en perturbant la production d'ARNm.