Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Polycystin-1 Antibody (7E12) is a high quality monoclonal Polycystin-1 antibody (also designated PKD1 antibody, or PC1 antibody) suitable for the detection of the Polycystin-1 protein of mouse, rat and human origin. Polycystin-1 Antibody (7E12) is available as both the non-conjugated anti-Polycystin-1 antibody form, as well as multiple conjugated forms of anti-Polycystin-1 antibody, including agarose, PE, FITC and multiple Alexa Fluor® conjugates. Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of cysts in kidney tubules as well as in liver and pancreas tissues. Cells within these cysts display abnormalities in proliferation and polarity. The integral membrane protein, Polycystin-1 (PKD1) is mutated in a majority of patients with ADPKD. Polycystin-1 is expressed in renal tubular epithelial cells and colocalizes with cell and focal adhesion proteins, including E-cadherin, catenins, vinculin, and paxillin, to focal areas in order to form a larger multiprotein complex. Polycystin-1 is posttranslationally modified by tyrosine phosphorylation and associates with Polycystin-2 (PKD2) to mediate AP-1 expression, which suggests that Polycystin-1 is involved in cell-cell and cell-matrix interactions to control cell proliferation and polarity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences