PFKL para análisis funcionales de las repuestas celulares a PFK
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), liver (PFKL) and platelet (PFKP). PFKL (phosphofructokinase, liver), also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney. Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, which suggests that PFKL may play a role in glucose-induced insulin secretion. PFKL is expressed at high levels in Down's syndrome (DS) patients, suggesting a possible role for PFKL in the pathogenesis of DS.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.