Date published: 2026-1-8

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PFK-1 Antibodies

Santa Cruz Biotechnology features a diverse variety of PFK-1 monoclonal antibodies for research focused on phosphofructokinase-1 in cellular metabolism. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Phosphofructokinase-1 functions as a key regulatory enzyme in the glycolytic pathway, facilitating the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. As a central component in energy production and metabolic regulation, phosphofructokinase-1 maintains essential cellular function and homeostasis. Research has shown that alterations in phosphofructokinase-1 activity are associated with various metabolic disorders and cancer, highlighting its significance as a target for therapeutic intervention. Understanding phosphofructokinase-1 regulation and function can provide valuable insights into metabolic disease mechanisms and potential treatment strategies. Investigating phosphofructokinase-1 activity patterns helps reveal crucial aspects of cellular energy metabolism and its role in disease progression. Exploring phosphofructokinase-1 expression levels across different tissues can uncover new therapeutic approaches. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of metabolic pathways and their impact on human health.

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PFK-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PFK-1 Antibody (G-11)

sc-166722mouse IgG2b κ676-730 (h)WB, IP, IF, ELISAm, r, h
31
(4)

PFK-1 Antibody (E-4)

sc-377346mouse IgG3 κ681-715 (h)WB, IP, IF, IHC(P), ELISAm, r, h
26
(5)

PFK-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PFK-1 CRISPR/Cas9 KO Plasmid (h)

sc-401023hGene KnockoutGFP0
(0)

PFK-1 CRISPR/Cas9 KO Plasmid (h2)

sc-401023-KO-2hGene KnockoutGFP0
(0)

PFK-1 HDR Plasmid (h2)

sc-401023-HDR-2hHomology Directed RepairPuromycin0
(0)

PFK-1 Double Nickase Plasmid (h)

sc-401023-NIChGene KnockoutPuromycin0
(0)

PFK-1 Double Nickase Plasmid (h2)

sc-401023-NIC-2hGene KnockoutPuromycin0
(0)

PFK-1 CRISPR/Cas9 KO Plasmid (m)

sc-422205mGene KnockoutGFP0
(0)

PFK-1 HDR Plasmid (m)

sc-422205-HDRmHomology Directed RepairPuromycin0
(0)

PFK-1 Double Nickase Plasmid (m)

sc-422205-NICmGene KnockoutPuromycin0
(0)

PFK-1 Double Nickase Plasmid (m2)

sc-422205-NIC-2mGene KnockoutPuromycin0
(0)

PFK-1 CRISPR/Cas9 KO Plasmid (r)

sc-437376rGene KnockoutGFP0
(0)

PFK-1 HDR Plasmid (r)

sc-437376-HDRrHomology Directed RepairPuromycin0
(0)

PFK-1 Double Nickase Plasmid (r)

sc-437376-NICrGene KnockoutPuromycin0
(0)

PFK-1 Double Nickase Plasmid (r2)

sc-437376-NIC-2r2Gene KnockoutPuromycin0
(0)

PFK-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PFK-1 CRISPR Activation Plasmid (h)

sc-401023-ACThGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 CRISPR Activation Plasmid (h2)

sc-401023-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (h)

sc-401023-LAChGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (h2)

sc-401023-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 CRISPR Activation Plasmid (m)

sc-422205-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 CRISPR Activation Plasmid (m2)

sc-422205-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (m)

sc-422205-LACmGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (m2)

sc-422205-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 CRISPR Activation Plasmid (r)

sc-437376-ACTrGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 CRISPR Activation Plasmid (r2)

sc-437376-ACT-2r2Gene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (r)

sc-437376-LACrGene ActivationPuro, Blast, Hygro0
(0)

PFK-1 Lentiviral Activation Particles (r2)

sc-437376-LAC-2r2Gene ActivationPuro, Blast, Hygro0
(0)

PFK-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PFK-1 siRNA (h)

sc-44561hGene SilencingN/A
2
(0)

PFK-1 shRNA Plasmid (h)

sc-44561-SHhGene SilencingPuromycin
2
(0)

PFK-1 shRNA (h) Lentiviral Particles

sc-44561-VhGene SilencingPuromycin
2
(0)

PFK-1 siRNA (m)

sc-44562mGene SilencingN/A0
(0)

PFK-1 shRNA Plasmid (m)

sc-44562-SHmGene SilencingPuromycin0
(0)

PFK-1 shRNA (m) Lentiviral Particles

sc-44562-VmGene SilencingPuromycin0
(0)