Anti-NEDD1 Anticuerpo H-3 es un monoclonal de ratón IgG1 κ NEDD1 Anticuerpo, ver las 1 publicaciones, proporcionado como 200 µg/ml
producido contra los amino ácidos 61-360 localizados cerca del N-terminus de NEDD1 de origen human
NEDD1 Anticuerpo (H-3) es recomendado para detectar NEDD1 de mouse, rat y human origen, mediante WB, IP, IF y ELISA
NEDD1 Anticuerpo (H-3) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de NEDD1 (H-3): sc-398733.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NEDD1 Antibody (H-3) for WB applications. These reagents are now offered in bundles with NEDD1 Antibody (H-3) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
NEDD1 Antibody (H-3) is a high quality monoclonal NEDD1 antibody (also designated NEDD1 antibody) suitable for the detection of the NEDD1 protein of mouse, rat and human origin. NEDD1 Antibody (H-3) is available as both the non-conjugated anti-NEDD1 antibody form, as well as multiple conjugated forms of anti-NEDD1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. NEDD1 (neural precursor cell expressed, developmentally down-regulated 1), also known as GCP-WD, is a homolog of the Drosophila protein known as Dgp71WD. It is a ubiquitously expressed, evolutionarily conserved protein and contains eight WD40 repeats and a coiled coil domain at the C-terminus. NEDD1 is a subunit of the γ-tubulin ring complex (γTuRC) and plays an important role in mitosis. During mitosis NEDD1 is phosphorylated and functions in forming the association of γ-tubulin with the spindle. The state of phosphorylation of NEDD1 is also important for determining its cellular localization. NEDD1 is responsible for targeting γTuRC to the centrosome and spindle and is therefore required for centrosomal and chromatin-mediated microtubule nucleation. The inhibition of NEDD1 results in the loss of γTuRC from the centrosome and a sequential loss of microtubule nucleation. Due to its critical role in mitosis, NEDD1 may be a potential target for anticancer therapies.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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