Glycophorin C Antibody (3H2009): sc-71161

Glycophorin C Antibody (3H2009) is a mouse monoclonal IgG1 antibody that detects Glycophorin C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Glycophorin C is a crucial sialoglycoprotein located on the surface of human erythrocytes, where Glycophorin C plays a significant role in maintaining the structural integrity of red blood cells and facilitating cell-cell interactions. Glycophorin C (3H2009) antibody helps researchers study a protein essential for proper erythrocyte functioning, preventing hemolysis and contributing to cell membrane stability. The Glycophorin C gene, which maps to chromosome 2q14.3, can produce two isoforms through alternative splicing, with Isoform 1 encoding the full-length 128 amino acid protein and Isoform 2, also known as Glycophorin D, encoding a shorter 109 amino acid variant associated with the Yus subtype of the Gerbich phenotype. The presence of these isoforms and their specific interactions with other membrane proteins are vital for understanding blood group phenotypes and their implications in transfusion medicine and disease susceptibility. Anti-Glycophorin C antibody (3H2009) serves as an invaluable tool for researchers studying erythrocyte biology and blood group antigen expression.

The preferred Glycophorin C antibody is Glycophorin C Antibody (E5): sc-59185.