glycogen synthase 1 Antibody (GS-7H5): sc-81173
- glycogen synthase 1 Antibody (GS-7H5) is a mouse monoclonal IgG1 κ glycogen synthase 1 antibody, cited in 11 publications, provided at 200 µg/ml
- raised against glycogen sythase from skeletal muscle of rabbit origin
- glycogen synthase 1 Antibody (GS-7H5) is recommended for detection of glycogen synthase 1 of mouse, rat and rabbit origin by WB, IP and IF
- Anti-glycogen synthase 1 Antibody (GS-7H5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for glycogen synthase 1 Antibody (GS-7H5) for WB applications. These reagents are now offered in bundles with glycogen synthase 1 Antibody (GS-7H5) (see ordering information below).
QUICK LINKS
Glycogen synthase 1 Antibody (GS-7H5) is a mouse monoclonal IgG1 kappa light chain antibody that detects glycogen synthase 1 protein of mouse, rat, and rabbit origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-glycogen synthase 1 antibody (GS-7H5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glycogen synthase 1 plays a crucial role in glycogen biosynthesis, transferring glycosyl residues from UDP-Glucose to the nonreducing end of α-1,4-glucan, which is essential for energy storage in cells. This protein exists in two forms: a liver variant and a muscle variant, each tailored to meet the metabolic demands of their respective tissues. The liver form helps maintain blood glucose homeostasis, responding to nutritional signals to regulate glucose levels in the bloodstream, while the muscle form activates during physical activity, providing energy for muscle contraction. Mutations in the gene encoding liver glycogen synthase can lead to glycogen storage disease type 0 (GSD0), a condition characterized by fasting hypoglycemia and impaired glycogen synthesis, highlighting glycogen synthase 1′s significance in metabolic health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
glycogen synthase 1 Antibody (GS-7H5) References:
- Glycogen and its metabolism. | Roach, PJ. 2002. Curr Mol Med. 2: 101-20. PMID: 11949930
- Control of glycogen deposition. | Ferrer, JC., et al. 2003. FEBS Lett. 546: 127-32. PMID: 12829248
- Hepatic glycogen synthase deficiency: an infrequently recognized cause of ketotic hypoglycemia. | Weinstein, DA., et al. 2006. Mol Genet Metab. 87: 284-8. PMID: 16337419
- The primary structure of rat liver glycogen synthase deduced by cDNA cloning. Absence of phosphorylation sites 1a and 1b. | Bai, G., et al. 1990. J Biol Chem. 265: 7843-8. PMID: 2110561
- Identification of the 38-kDa subunit of rabbit skeletal muscle glycogen synthase as glycogenin. | Pitcher, J., et al. 1987. Eur J Biochem. 169: 497-502. PMID: 3121316
- Primary structure of human liver glycogen synthase deduced by cDNA cloning. | Nuttall, FQ., et al. 1994. Arch Biochem Biophys. 311: 443-9. PMID: 8203908
- Control of glycaemia. | Gerich, JE. 1993. Baillieres Clin Endocrinol Metab. 7: 551-86. PMID: 8379904
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
glycogen synthase 1 Antibody (GS-7H5) | sc-81173 | 200 µg/ml | $322.00 | |||
glycogen synthase 1 Antibody (GS-7H5): m-IgG Fc BP-HRP Bundle | sc-528701 | 200 µg Ab; 10 µg BP | $361.00 | |||
glycogen synthase 1 Antibody (GS-7H5): m-IgGκ BP-HRP Bundle | sc-521168 | 200 µg Ab, 40 µg BP | $361.00 | |||
glycogen synthase 1 Antibody (GS-7H5): m-IgG1 BP-HRP Bundle | sc-543072 | 200 µg Ab; 20 µg BP | $361.00 | |||
glycogen synthase 1 Antibody (GS-7H5) AC | sc-81173 AC | 500 µg/ml, 25% agarose | $424.00 | |||
glycogen synthase 1 Antibody (GS-7H5) HRP | sc-81173 HRP | 200 µg/ml | $322.00 | |||
glycogen synthase 1 Antibody (GS-7H5) FITC | sc-81173 FITC | 200 µg/ml | $336.00 | |||
glycogen synthase 1 Antibody (GS-7H5) PE | sc-81173 PE | 200 µg/ml | $349.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 488 | sc-81173 AF488 | 200 µg/ml | $364.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 546 | sc-81173 AF546 | 200 µg/ml | $364.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 594 | sc-81173 AF594 | 200 µg/ml | $364.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 647 | sc-81173 AF647 | 200 µg/ml | $364.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 680 | sc-81173 AF680 | 200 µg/ml | $364.00 | |||
glycogen synthase 1 Antibody (GS-7H5) Alexa Fluor® 790 | sc-81173 AF790 | 200 µg/ml | $364.00 |