Anti-API5 Anticuerpo E-12 es un monoclonal de ratón IgG1 (kappa light chain) API5 Anticuerpo proporcionado como 200 µg/ml
producido contra los amino ácidos 1-300 localizados en el N-terminus de origen API5 of human
API5 Anticuerpo (E-12) es recomendado para detectar API5 de mouse, rat y human origen, mediante WB, IP, IF y ELISA
API5 Anticuerpo (E-12) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de API5 (E-12): sc-374528.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for API5 Antibody (E-12) for WB applications. This reagent is now offered in a bundle with API5 Antibody (E-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
API5 Antibody (E-12) is a high quality monoclonal API5 antibody (also designated API5 antibody) suitable for the detection of the API5 protein of mouse, rat and human origin. API5 Antibody (E-12) is available as both the non-conjugated anti-API5 antibody form, as well as multiple conjugated forms of anti-API5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. API5 (apoptosis inhibitor 5), also known as AAC11 (antiapoptosis clone 11 protein), FIF (fibroblast growth factor 2-interacting factor), MIG8, XAGL or API5L1, is a widely expressed antiapoptotic nuclear protein that is highly conserved from flies to humans. API5 contains a nuclear localization sequence, an LxxLL motif, a leucine zipper domain and a transactivation domain flanked by two acidic domains. API5 forms a nuclear localized complex with FGF-2 and may mediate FGF-2-dependent signaling. API5 is believed to function as a transcription regulator and is able to regulate the synthesis of MMP-2 (matrix metalloproteinase-2). In addition, API5 is known to specifically suppress E2F-dependent apoptosis. It is expressed in a variety of cancer cell lines and its expression is linked to tumor progression and the degree of malignancy.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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