Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
4E-BP3 Antibody (4-RY9) is a high quality monoclonal 4E-BP3 antibody (also designated 4E-BP3 antibody) suitable for the detection of the 4E-BP3 protein of human origin. 4E-BP3 Antibody (4-RY9) is available as the non-conjugated anti-4E-BP3 antibody. The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. These interactions are facilitated, in part, by the eukaryotic initiation factor 4 family (eIF4) of proteins that are involved in the early initiation of protein synthesis. 4E-BP3, also known as EIF4EBP3 (eukaryotic translation initiation factor 4E binding protein 3), is a 100 amino acid protein that belongs to the eIF4E-binding protein family. Highly expressed in heart, kidney, pancreas and skeletal muscle and present at lower levels in thymus and brain, 4E-BP3 interacts with eIF4E and, via this interaction, regulates eIF4E activity, specifically by preventing the incorporation of eIF4E into the eIF4 complex. 4E-BP3 is subject to post-translational phosphorylation and is encoded by a gene which maps to human chromosome 5.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Could this antibody potentially be crossreactive for mouse 4eBP? Could try out a sample?
Preguntado por: Bernhard
Thank you for your question. This antibody has not yet been tested in mouse samples and so it is not a recommended species at this time. This antibody is currently only available for purchase (no samples available).
Respondida por: Technical Support
Fecha de publicación: 2019-06-15
For Western Blot, is it recommended to use denatured or non-denatured conditions with 4E-BP3 (4-RY9): sc-134232 antibody?
Preguntado por: Germaine
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn