Date published: 2026-7-19

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Tiam Antibodies

Santa Cruz Biotechnology features a diverse variety of Tiam monoclonal antibodies for advanced research in cell signaling and cancer biology. Tiam Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Tiam, or T-lymphoma invasion and metastasis 1, is a guanine nucleotide exchange factor that plays a crucial role in regulating cell migration and invasion through interaction with Rho GTPases. Tiam significantly influences cancer progression by affecting the epithelial-mesenchymal transition (EMT) and contributing to the metastatic potential of tumor cells. Research has shown that Tiam expression levels correlate with cancer progression in multiple tumor types. Understanding Tiam's molecular mechanisms and signaling pathways is essential for developing targeted therapies and improving treatment strategies for various cancers. Investigating Tiam's role in cell motility provides valuable insights into tumor metastasis mechanisms. Researchers can explore cellular migration patterns and metastatic behavior through detailed analysis of Tiam activity. Santa Cruz Biotechnology monoclonal antibodies support cutting-edge cancer research, enabling scientists to advance our understanding of tumor progression and develop more effective therapeutic approaches.

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Tiam Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Tiam1 Antibody (E-7)

sc-393315mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
10
(8)

Tiam1 Antibody (F-11)

sc-377355mouse IgM κ2-27 (m)WB, IP, IF, ELISAm, r, h
1
(1)

Tiam1 Antibody (G-1)

sc-393176mouse IgM κ1-300 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Tiam2 Antibody (C-5)

sc-514090mouse IgM κ1006-1026 (h)WB, IP, IF, ELISAm, r, h

new

(2)

Tiam siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tiam1 siRNA (h)

sc-36669hGene SilencingN/A
8
(0)

Tiam1 shRNA Plasmid (h)

sc-36669-SHhGene SilencingPuromycin
8
(0)

Tiam1 shRNA (h) Lentiviral Particles

sc-36669-VhGene SilencingPuromycin
8
(0)

Tiam1 siRNA (m)

sc-36670mGene SilencingN/A
1
(0)

Tiam1 shRNA Plasmid (m)

sc-36670-SHmGene SilencingPuromycin
1
(0)

Tiam1 shRNA (m) Lentiviral Particles

sc-36670-VmGene SilencingPuromycin
1
(0)

Tiam2 siRNA (h)

sc-41736hGene SilencingN/A
1
(0)

Tiam2 shRNA Plasmid (h)

sc-41736-SHhGene SilencingPuromycin
1
(0)

Tiam2 shRNA (h) Lentiviral Particles

sc-41736-VhGene SilencingPuromycin
1
(0)

Tiam2 siRNA (m)

sc-41737mGene SilencingN/A0
(0)

Tiam2 shRNA Plasmid (m)

sc-41737-SHmGene SilencingPuromycin0
(0)

Tiam2 shRNA (m) Lentiviral Particles

sc-41737-VmGene SilencingPuromycin0
(0)

Tiam CRISPR Knockout (KO) and HDR Plasmids

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Tiam1 CRISPR/Cas9 KO Plasmid (h)

sc-400674Gene Knockouth0
(0)

Tiam1 HDR Plasmid (h)

sc-400674-HDRHomology Directed Repairh0
(0)

Tiam2 CRISPR/Cas9 KO Plasmid (h)

sc-404326Gene Knockouth0
(0)

Tiam2 HDR Plasmid (h)

sc-404326-HDRHomology Directed Repairh0
(0)

Tiam CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Tiam2 Double Nickase Plasmid (h)

sc-404326-NICGene Knockouth0
(0)

Tiam2 Double Nickase Plasmid (h2)

sc-404326-NIC-2Gene Knockouth0
(0)

Tiam CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Tiam1 CRISPR Activation Plasmid (h)

sc-400674-ACTGene Activationh0
(0)