Slp5 Activadores
Synaptotagmin-like protein 5 (Slp5) belongs to the synaptotagmin family, which is known for its involvement in the regulation of membrane trafficking and neurotransmitter release. Members of this family typically contain C2 domains that bind to calcium and phospholipids, which are key in their role in vesicle trafficking and exocytosis.As a "like" member of the synaptotagmin family, Slp5 shares homology with classical synaptotagmins but can have distinct functions or regulatory mechanisms. These proteins are often involved in the fine-tuning of vesicle-mediated transport and membrane fusion events, which are critical for processes such as synaptic transmission, hormone release, and other cellular secretion mechanisms.
The specific function of Slp5 can vary by cell type and organism. In general, synaptotagmin-like proteins are thought to help coordinate the docking and release of vesicles in response to increases in intracellular calcium levels, a crucial step in ensuring rapid and precise signal transmission across synapses or release of substances from a cell. These proteins can interact with SNARE proteins and other components of the vesicle fusion machinery, modulating their function in a calcium-dependent manner.Mutations or dysregulation of synaptotagmin-like proteins, including Slp5, could potentially lead to various neurological disorders or contribute to the pathology of metabolic diseases, as vesicle trafficking is critical in many signaling pathways and cellular processes.
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| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
La PMA activa la proteína quinasa C (PKC), que puede influir en la exocitosis de las vesículas sinápticas, afectando potencialmente a las vías relacionadas con SYTL5. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
La forskolina activa la adenilato ciclasa, aumentando los niveles de AMPc, lo que puede modular indirectamente la actividad de SYTL5 a través de vías dependientes de PKA. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Este compuesto altera el aparato de Golgi y podría afectar al tráfico de proteínas como SYTL5. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
El nocodazol altera los microtúbulos y puede influir en el tráfico intracelular, afectando potencialmente a la función de SYTL5. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
La monensina es un ionóforo que altera los gradientes iónicos intracelulares, afectando potencialmente al tráfico de vesículas relacionado con SYTL5. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
En tant qu'inhibiteur de PI3K, la wortmannine peut indirectement affecter SYTL5 en modifiant les voies de signalisation intracellulaires. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Se trata de otro inhibidor de PI3K, que podría afectar a las vías de señalización relacionadas con la actividad de SYTL5. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Como inhibidor de mTOR, la rapamicina puede afectar a varios procesos celulares, influyendo potencialmente en la función de SYTL5. | ||||||
Benzyl mercaptan | 100-53-8 | sc-353053 sc-353053A | 25 g 100 g | $42.00 $64.00 | ||
En tant que matériau biologique, le rôle du NGF dans le développement et la fonction neuronale peut influencer indirectement le SYTL5. | ||||||
Bis(pinacolato)diboron | 73183-34-3 | sc-252467 sc-252467A | 1 g 5 g | $44.00 $82.00 | ||
Comme le NGF, le PDGF est un facteur biologique qui peut moduler les voies de signalisation cellulaires affectant SYTL5. | ||||||