Periphilin 1 is a protein encoded by the "PPHLN1" gene in humans. It is involved in multiple cellular processes, particularly in the formation and maintenance of the cellular cytoskeleton and in the regulation of gene expression.As its name suggests, periphilin 1 is localized primarily in the periphery of the cell, where it interacts with various components of the cytoskeleton. The cytoskeleton is a network of fibers that provides structural support to the cell, facilitates cellular movement, and plays a role in intracellular transport and cell division. By interacting with the cytoskeleton, periphilin 1 contributes to maintaining the structural integrity and dynamic nature of cells.
In addition to its structural role, periphilin 1 is involved in the regulation of gene expression. It has been found to associate with transcription factors and components of the transcription machinery, suggesting a role in modulating the transcription of specific genes. This regulation of gene expression is vital for various cellular functions, including differentiation, response to external stimuli, and cell cycle control.Periphilin 1 has also been studied in the context of its involvement in certain pathological conditions. Alterations in its expression or function have been associated with some skin disorders, where it may affect the structure and function of epidermal cells.Overall, periphilin 1 is a multifunctional protein with roles in maintaining cellular structure and regulating gene expression. Its diverse functions highlight its importance in fundamental cellular processes and its relevance in certain diseases.
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| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
La 5-azacitidina, un inhibidor de la metiltransferasa del ADN, altera la estructura de la cromatina y puede afectar indirectamente a la función de la perifilina 1 en la regulación de la transcripción. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Como inhibidor de la histona desacetilasa, la tricostatina A afecta a la remodelación de la cromatina, influyendo potencialmente en la función de la perifilina 1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Otro inhibidor de la histona desacetilasa, el SAHA, puede afectar a la estructura de la cromatina y repercutir indirectamente en la actividad de la perifilina 1. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
Un inhibidor específico de HDAC3, RGFP966, puede afectar indirectamente a la estructura de la cromatina y a la función de Perifilina 1. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Un inhibidor selectivo de HDAC, MS-275, puede influir en la remodelación de la cromatina y afectar potencialmente a la actividad de Perifilina 1. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibidor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
Un inhibidor de la histona metiltransferasa G9a, el BIX-01294, puede alterar la metilación de las histonas, lo que podría influir en la función de la perifilina 1. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
El C646, un inhibidor de la histona acetiltransferasa, puede afectar indirectamente a la perifilina 1 al influir en la acetilación de histonas y la estructura de la cromatina. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Un inhibidor del bromodominio BET, JQ1, puede afectar a la arquitectura de la cromatina e influir indirectamente en la actividad de la perifilina 1. | ||||||
Methylstat | 1310877-95-2 | sc-507374 | 10 mg | $480.00 | ||
Un inhibidor de la desmetilasa de histonas que contiene el dominio Jumonji C, Methylstat, puede influir indirectamente en la actividad de Perifilina 1 al afectar a la metilación de histonas. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $126.00 | 5 | |
La chaetocina, un inhibidor dirigido a la histona metiltransferasa SUV39H1, puede influir indirectamente en el papel de la perifilina 1 en la organización de la cromatina. | ||||||