NCDN inhibitors belong to a fascinating chemical class that has garnered significant attention and scientific interest in recent years. These inhibitors are compounds specifically designed and synthesized to target a protein called NCDN, which plays a vital role in various cellular processes. The acronym NCDN stands for neuronal calcium-binding protein and dendritic spine maturation factor, indicating its involvement in neuronal development and synaptic plasticity. NCDN inhibitors possess a unique molecular structure that allows them to interact with the active site of the NCDN protein. By binding to this active site, the inhibitors effectively hinder the normal function of NCDN and disrupt the associated signaling pathways and molecular cascades in which NCDN is involved. This interference at the molecular level offers researchers a valuable tool for investigating the intricate mechanisms underlying cellular processes regulated by NCDN.
The discovery and characterization of NCDN inhibitors have provided scientists with a means to explore the physiological consequences of inhibiting NCDN activity. Through comprehensive studies and meticulous experiments, researchers aim to unravel the precise molecular and physiological effects induced by NCDN inhibition. These investigations help elucidate the role of NCDN in various cellular contexts and shed light on its significance in neuronal development, synaptic plasticity, and other cellular processes. The chemical class of NCDN inhibitors represents a remarkable advancement in our understanding of cellular biology. Their specific and targeted action on NCDN provides scientists with an opportunity to explore the intricate interactions between this protein and other molecular components within cells. By deciphering the underlying molecular mechanisms associated with NCDN inhibition, researchers can gain valuable insights into fundamental cellular processes and pathways. Moreover, the availability of NCDN inhibitors opens up new avenues for experimental studies in scientific research. Researchers can utilize these inhibitors to manipulate NCDN activity and observe the resulting effects on cellular function and behavior. This knowledge can contribute to a deeper understanding of the fundamental principles governing cellular processes and pave the way for further discoveries in the field of molecular biology.
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| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
Donepezil | 120014-06-4 | sc-279006 | 10 mg | $73.00 | 3 | |
Inhibidor de la acetilcolinesterasa utilizado en la enfermedad de Alzheimer, mejora la neurotransmisión al inhibir la degradación de la acetilcolina. | ||||||
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $280.00 | 1 | |
El MLN4924 es un inhibidor potente y selectivo de la NAE que ha demostrado actividad anticancerosa. Bloquea la activación de NEDD8 e interrumpe la función de las ligasas E3 Cullin-RING, lo que conduce a la estabilización de sus proteínas sustrato e induce la detención del ciclo celular y la apoptosis en las células cancerosas. | ||||||
Memantine hydrochloride | 41100-52-1 | sc-203628 | 50 mg | $68.00 | 4 | |
Antagonista de los receptores NMDA utilizado en la enfermedad de Alzheimer, modula la señalización del glutamato para reducir la excitotoxicidad. | ||||||
MLN7243 | 1450833-55-2 | sc-507338 | 5 mg | $340.00 | ||
El TAK-243 es un inhibidor de la NQO1 de segunda generación desarrollado como una versión mejorada del MLN492. Presenta una mayor potencia y selectividad, con potencial para superar ciertas limitaciones observadas con el MLN4924. | ||||||
(S)-Rivastigmine | 123441-03-2 | sc-472567 | 500 mg | $300.00 | ||
Inhibidor de la acetilcolinesterasa para el Alzheimer, mejora la transmisión colinérgica. | ||||||
Galanthamine | 357-70-0 | sc-218556 | 10 mg | $320.00 | ||
Inhibidor de la acetilcolinesterasa, también modula los receptores nicotínicos para mejorar la función cognitiva en el Alzheimer. | ||||||
GSK 923295 | 1088965-37-0 | sc-490136 | 5 mg | $290.00 | ||
El GSK923295 es un inhibidor selectivo de los NAE que ha demostrado actividad antitumoral en varios modelos de cáncer. Inhibe la enzima activadora de la NEDD8, lo que provoca la acumulación de sustratos de la ligasa E3 Cullin-RING e induce la detención del ciclo celular y la apoptosis. | ||||||
Levodopa | 59-92-7 | sc-205372 sc-205372A | 5 g 25 g | $53.00 $168.00 | 9 | |
Precursor de la dopamina utilizado en la enfermedad de Parkinson, repone los niveles de dopamina en el cerebro. | ||||||
S(−)-Carbidopa | 28860-95-9 | sc-200749 sc-200749A | 25 mg 100 mg | $94.00 $270.00 | 5 | |
Potencia la eficacia de la L-DOPA bloqueando su conversión en dopamina fuera del cerebro. | ||||||
Riluzole | 1744-22-5 | sc-201081 sc-201081A sc-201081B sc-201081C | 20 mg 100 mg 1 g 25 g | $20.00 $189.00 $209.00 $311.00 | 1 | |
Modifie la signalisation du glutamate et peut ralentir la progression de la maladie dans la SLA (sclérose latérale amyotrophique). | ||||||