Date published: 2026-7-14

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MKP Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MKP Antibodies for advanced research in cellular signaling. MKP Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Mitogen-activated protein kinases (MAPKs) play a crucial role in transmitting signals from the cell surface to the nucleus, influencing processes such as cell growth, differentiation, and apoptosis. MKPs (MAPK phosphatases) are essential for regulating MAPK activity, ensuring that cellular responses are appropriately modulated. Understanding the function of MKPs is vital for elucidating their roles in various diseases, including cancer and inflammatory disorders. MKP monoclonal antibodies enable precise detection and analysis of MAPK signaling pathways in both normal and pathological conditions. Researchers can investigate specific protein interactions and cellular localization patterns using multiple experimental approaches. The high specificity of MKP monoclonal antibodies supports reliable and reproducible results across different research applications. Santa Cruz Biotechnology monoclonal antibodies for MKP research contribute to advancing our understanding of cellular signaling mechanisms and potential therapeutic targets.

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MKP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MKP-1/DUSP1 Antibody (E-6)

sc-373841mouse IgG2b κ321-365 (m)WB, IP, IF, ELISAm, r, h
26
(9)

MKP-2 Antibody (F-10)

sc-17821mouse IgG2a κ78-144 (h)WB, IP, IF, ELISAm, r, h
4
(12)

MKP-2 Antibody (48)

sc-135991mouse IgG113-127 (r)WB, IP, IFm, r, h
2
(5)

MKP-3 Antibody (F-12)

sc-377070mouse IgG1 κ353-381 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(14)

MKP-3 Antibody (G-11)

sc-137245mouse IgG1 κ1-130 (h)WB, IP, IF, ELISAm, r, h
2
(2)

MKP-3 Antibody (G-12)

sc-166041mouse IgG2b κ1-130 (h)WB, IP, IF, ELISAm, r, h
1
(1)

MKP-3 Antibody (G-4)

sc-137246mouse IgG2a κ1-130 (h)WB, IP, IF, ELISAm, r, h
5
(3)

MKP-4 Antibody (D-3)

sc-137010mouse IgG2a κ340-384 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(3)

MKP-5 Antibody (G-10)

sc-374276mouse IgG2a κ1-205 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

MKP-6 Antibody (4B5-E6)

sc-517023mouse IgG2a κFL (h)WB, IP, IF, ELISAh

new

(1)

MKP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MKP-2 siRNA (h)

sc-38998hGene SilencingN/A
3
(1)

MKP-2 shRNA Plasmid (h)

sc-38998-SHhGene SilencingPuromycin
3
(1)

MKP-2 shRNA (h) Lentiviral Particles

sc-38998-VhGene SilencingPuromycin
3
(1)

MKP-2 siRNA (m)

sc-38999mGene SilencingN/A
1
(0)

MKP-2 shRNA Plasmid (m)

sc-38999-SHmGene SilencingPuromycin
1
(0)

MKP-2 shRNA (m) Lentiviral Particles

sc-38999-VmGene SilencingPuromycin
1
(0)

MKP-3 siRNA (h)

sc-39000hGene SilencingN/A
3
(1)

MKP-3 shRNA Plasmid (h)

sc-39000-SHhGene SilencingPuromycin
3
(1)

MKP-3 shRNA (h) Lentiviral Particles

sc-39000-VhGene SilencingPuromycin
3
(1)

MKP-3 siRNA (m)

sc-39001mGene SilencingN/A
6
(0)

MKP-3 shRNA Plasmid (m)

sc-39001-SHmGene SilencingPuromycin
6
(0)

MKP-3 shRNA (m) Lentiviral Particles

sc-39001-VmGene SilencingPuromycin
6
(0)

MKP-4 siRNA (h)

sc-39002hGene SilencingN/A0
(0)

MKP-4 shRNA Plasmid (h)

sc-39002-SHhGene SilencingPuromycin0
(0)

MKP-4 shRNA (h) Lentiviral Particles

sc-39002-VhGene SilencingPuromycin0
(0)

MKP-4 siRNA (m)

sc-39003mGene SilencingN/A
2
(0)

MKP-4 shRNA Plasmid (m)

sc-39003-SHmGene SilencingPuromycin
2
(0)

MKP-4 shRNA (m) Lentiviral Particles

sc-39003-VmGene SilencingPuromycin
2
(0)

MKP-5 siRNA (h)

sc-61048hGene SilencingN/A
2
(0)

MKP-5 shRNA Plasmid (h)

sc-61048-SHhGene SilencingPuromycin
2
(0)

MKP-5 shRNA (h) Lentiviral Particles

sc-61048-VhGene SilencingPuromycin
2
(0)

MKP-5 siRNA (m)

sc-61049mGene SilencingN/A0
(0)

MKP-5 shRNA Plasmid (m)

sc-61049-SHmGene SilencingPuromycin0
(0)

MKP-5 shRNA (m) Lentiviral Particles

sc-61049-VmGene SilencingPuromycin0
(0)

MKP-6 siRNA (h)

sc-61050hGene SilencingN/A0
(0)

MKP-6 shRNA Plasmid (h)

sc-61050-SHhGene SilencingPuromycin0
(0)

MKP-6 shRNA (h) Lentiviral Particles

sc-61050-VhGene SilencingPuromycin0
(0)

MKP-6 siRNA (m)

sc-61051mGene SilencingN/A0
(0)

MKP-6 shRNA Plasmid (m)

sc-61051-SHmGene SilencingPuromycin0
(0)

MKP-6 shRNA (m) Lentiviral Particles

sc-61051-VmGene SilencingPuromycin0
(0)

MKP-7 siRNA (h)

sc-61052hGene SilencingN/A
2
(0)

MKP-7 shRNA Plasmid (h)

sc-61052-SHhGene SilencingPuromycin
2
(0)

MKP-7 shRNA (h) Lentiviral Particles

sc-61052-VhGene SilencingPuromycin
2
(0)

MKP-7 siRNA (m)

sc-61053mGene SilencingN/A0
(0)

MKP-7 shRNA Plasmid (m)

sc-61053-SHmGene SilencingPuromycin0
(0)

MKP-7 shRNA (m) Lentiviral Particles

sc-61053-VmGene SilencingPuromycin0
(0)

MKP-1/DUSP1 siRNA (h)

sc-35937hGene SilencingN/A
26
(1)

MKP-1/DUSP1 siRNA (h2)

sc-44312hGene SilencingN/A
1
(0)

MKP-1/DUSP1 shRNA Plasmid (h)

sc-35937-SHhGene SilencingPuromycin
26
(1)

MKP-1/DUSP1 shRNA Plasmid (h2)

sc-44312-SHhGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 shRNA (h) Lentiviral Particles

sc-35937-VhGene SilencingPuromycin
26
(1)

MKP-1/DUSP1 shRNA (h2) Lentiviral Particles

sc-44312-VhGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 siRNA (m)

sc-35938mGene SilencingN/A
11
(0)

MKP-1/DUSP1 shRNA Plasmid (m)

sc-35938-SHmGene SilencingPuromycin
11
(0)

MKP-1/DUSP1 shRNA (m) Lentiviral Particles

sc-35938-VmGene SilencingPuromycin
11
(0)

MKP-1/DUSP1 siRNA (r)

sc-156163rGene SilencingN/A
2
(0)

MKP-1/DUSP1 siRNA (bovine)

sc-270515bovineGene SilencingN/A
1
(0)

MKP-1/DUSP1 shRNA Plasmid (bovine)

sc-270515-SHbovineGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 shRNA (bovine) Lentiviral Particles

sc-270515-VbovineGene SilencingPuromycin
1
(0)

MKP CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MKP-2 CRISPR/Cas9 KO Plasmid (h2)

sc-401479-KO-2Gene Knockouth0
(0)

MKP-2 HDR Plasmid (h2)

sc-401479-HDR-2Homology Directed Repairh0
(0)

MKP-3 CRISPR/Cas9 KO Plasmid (h)

sc-400850Gene Knockouth0
(0)

MKP-4 CRISPR/Cas9 KO Plasmid (h)

sc-405872Gene Knockouth0
(0)

MKP-6 CRISPR/Cas9 KO Plasmid (h)

sc-406250Gene Knockouth0
(0)

MKP-7 CRISPR/Cas9 KO Plasmid (h)

sc-405727Gene Knockouth0
(0)

MKP-7 HDR Plasmid (h)

sc-405727-HDRHomology Directed Repairh0
(0)

MKP-1/DUSP1 CRISPR/Cas9 KO Plasmid (m)

sc-422507Gene Knockoutm0
(0)

MKP CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MKP-2 Double Nickase Plasmid (h)

sc-401479-NICGene Knockouth0
(0)

MKP-2 Double Nickase Plasmid (h2)

sc-401479-NIC-2Gene Knockouth0
(0)

MKP-3 Double Nickase Plasmid (h)

sc-400850-NICGene Knockouth0
(0)

MKP-3 Double Nickase Plasmid (h2)

sc-400850-NIC-2Gene Knockouth0
(0)

MKP-4 Double Nickase Plasmid (h)

sc-405872-NICGene Knockouth0
(0)

MKP-4 Double Nickase Plasmid (h2)

sc-405872-NIC-2Gene Knockouth0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (h)

sc-400243-NICGene Knockouth0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (h2)

sc-400243-NIC-2Gene Knockouth0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (m)

sc-422507-NICGene Knockoutm0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (m2)

sc-422507-NIC-2Gene Knockoutm0
(0)

MKP CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MKP-3 CRISPR Activation Plasmid (h)

sc-400850-ACTGene Activationh0
(0)

MKP-7 CRISPR Activation Plasmid (h)

sc-405727-ACTGene Activationh0
(0)

MKP-7 CRISPR Activation Plasmid (h2)

sc-405727-ACT-2Gene Activationh0
(0)

MKP-1/DUSP1 CRISPR Activation Plasmid (h)

sc-400243-ACTGene Activationh0
(0)

MKP-1/DUSP1 CRISPR Activation Plasmid (h2)

sc-400243-ACT-2Gene Activationh0
(0)