Date published: 2025-9-11

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LOC439950 Activadores

The term LOC439950 Activators refers to a class of chemical agents that specifically interact with and increase the activity of the protein product of the gene designated as LOC439950. This alphanumeric label indicates a locus or a specific position within the human genome that has been identified but whose gene product and associated functions may not be fully characterized. The 'LOC' prefix is commonly assigned to loci that are thought to represent putative protein-coding regions within the genome, and the succeeding number serves as a unique identifier for researchers to reference this specific genomic segment. Activators in this context are molecules that enhance the biological activity of the protein encoded by LOC439950. They may do so through various mechanisms, such as increasing the transcriptional rates of the gene, stabilizing the protein product to prolong its cellular lifespan, or facilitating its interactions with other proteins or biochemical pathways within the cell.

The discovery and development of LOC439950 activators would involve a multi-disciplinary approach, initially focusing on the characterization of the LOC439950 protein. If the protein's structure could be resolved through methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron microscopy, this would provide invaluable insights into potential binding sites for small molecule activators. These activators would be designed to bind to the protein with high specificity, thereby enhancing its natural activity without disrupting other cellular mechanisms. Subsequent steps would include the synthesis of a diverse chemical library, with each compound designed to interact with the identified binding sites on the LOC439950 protein. Sophisticated high-throughput screening techniques would then be employed to test these compounds for their ability to modulate the protein's activity. Hits from this screening would be subjected to an iterative process of chemical modification to fine-tune their properties, such as binding affinity, specificity, and the ability to positively modulate the LOC439950 protein's activity. Through this cycle of design, testing, and refinement, effective LOC439950 activators would be developed, each uniquely crafted to engage with the protein product of the LOC439950 gene and elevate its functional state within the cellular context.

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Nombre del productoNÚMERO DE CAS #Número de catálogoCantidadPrecioMENCIONESClasificación

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Puede influir en la vía de señalización Wnt, que puede alterar la transcripción de genes y afectar potencialmente a los niveles de ARNnc, incluidos los ARN antisentido.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Un inhibidor de la ADN metiltransferasa que puede causar la desmetilación del ADN, lo que puede activar la transcripción de ciertos ARN no codificantes.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

Un inhibidor no nucleósido de la ADN metiltransferasa que puede provocar la desmetilación del ADN y potenciar la transcripción de los ARNnc.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Un inhibidor de la histona desacetilasa que puede alterar la estructura de la cromatina, aumentando potencialmente la expresión de ncRNAs, incluidos los transcritos antisentido.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Un compuesto de origen vegetal que puede modular muchas vías de señalización e influir potencialmente en la expresión de los ARNnc a través de sus efectos epigenéticos.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Se ha demostrado que tiene un amplio impacto en la expresión génica, posiblemente afectando a la transcripción de los ncRNAs debido a sus capacidades de modulación epigenética.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
18
(3)

Como inhibidor de la histona desacetilasa, puede cambiar la dinámica de la cromatina y afectar potencialmente a la expresión de los ARNnc.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Un compuesto presente en las verduras crucíferas que puede afectar a la expresión génica y podría influir en los niveles de ARNnc a través de mecanismos epigenéticos.

(±)-Methyl Jasmonate

39924-52-2sc-205386
sc-205386A
sc-205386B
sc-205386C
sc-205386D
sc-205386E
sc-205386F
1 g
5 g
10 g
50 g
100 g
500 g
1 kg
$35.00
$103.00
$200.00
$873.00
$1638.00
$6942.00
$12246.00
(1)

Una hormona vegetal que puede influir en una amplia gama de patrones de expresión génica, incluyendo potencialmente la transcripción de ARN antisentido.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Otro inhibidor de la metiltransferasa del ADN que puede provocar la hipometilación del ADN y podría afectar a la transcripción de los ARNnc.