The term LOC439950 Activators refers to a class of chemical agents that specifically interact with and increase the activity of the protein product of the gene designated as LOC439950. This alphanumeric label indicates a locus or a specific position within the human genome that has been identified but whose gene product and associated functions may not be fully characterized. The 'LOC' prefix is commonly assigned to loci that are thought to represent putative protein-coding regions within the genome, and the succeeding number serves as a unique identifier for researchers to reference this specific genomic segment. Activators in this context are molecules that enhance the biological activity of the protein encoded by LOC439950. They may do so through various mechanisms, such as increasing the transcriptional rates of the gene, stabilizing the protein product to prolong its cellular lifespan, or facilitating its interactions with other proteins or biochemical pathways within the cell.
The discovery and development of LOC439950 activators would involve a multi-disciplinary approach, initially focusing on the characterization of the LOC439950 protein. If the protein's structure could be resolved through methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron microscopy, this would provide invaluable insights into potential binding sites for small molecule activators. These activators would be designed to bind to the protein with high specificity, thereby enhancing its natural activity without disrupting other cellular mechanisms. Subsequent steps would include the synthesis of a diverse chemical library, with each compound designed to interact with the identified binding sites on the LOC439950 protein. Sophisticated high-throughput screening techniques would then be employed to test these compounds for their ability to modulate the protein's activity. Hits from this screening would be subjected to an iterative process of chemical modification to fine-tune their properties, such as binding affinity, specificity, and the ability to positively modulate the LOC439950 protein's activity. Through this cycle of design, testing, and refinement, effective LOC439950 activators would be developed, each uniquely crafted to engage with the protein product of the LOC439950 gene and elevate its functional state within the cellular context.
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Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
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Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Puede influir en la vía de señalización Wnt, que puede alterar la transcripción de genes y afectar potencialmente a los niveles de ARNnc, incluidos los ARN antisentido. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Un inhibidor de la ADN metiltransferasa que puede causar la desmetilación del ADN, lo que puede activar la transcripción de ciertos ARN no codificantes. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
Un inhibidor no nucleósido de la ADN metiltransferasa que puede provocar la desmetilación del ADN y potenciar la transcripción de los ARNnc. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Un inhibidor de la histona desacetilasa que puede alterar la estructura de la cromatina, aumentando potencialmente la expresión de ncRNAs, incluidos los transcritos antisentido. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Un compuesto de origen vegetal que puede modular muchas vías de señalización e influir potencialmente en la expresión de los ARNnc a través de sus efectos epigenéticos. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Se ha demostrado que tiene un amplio impacto en la expresión génica, posiblemente afectando a la transcripción de los ncRNAs debido a sus capacidades de modulación epigenética. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Como inhibidor de la histona desacetilasa, puede cambiar la dinámica de la cromatina y afectar potencialmente a la expresión de los ARNnc. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Un compuesto presente en las verduras crucíferas que puede afectar a la expresión génica y podría influir en los niveles de ARNnc a través de mecanismos epigenéticos. | ||||||
(±)-Methyl Jasmonate | 39924-52-2 | sc-205386 sc-205386A sc-205386B sc-205386C sc-205386D sc-205386E sc-205386F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $35.00 $103.00 $200.00 $873.00 $1638.00 $6942.00 $12246.00 | ||
Una hormona vegetal que puede influir en una amplia gama de patrones de expresión génica, incluyendo potencialmente la transcripción de ARN antisentido. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Otro inhibidor de la metiltransferasa del ADN que puede provocar la hipometilación del ADN y podría afectar a la transcripción de los ARNnc. |