Date published: 2026-6-30

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IL-22R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IL-22R monoclonal antibodies for research focused on understanding the interleukin-22 receptor. IL-22R monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The interleukin-22 receptor mediates the effects of interleukin-22, a cytokine involved in immune responses and tissue homeostasis. IL-22R plays a significant role in regulating inflammation and maintaining epithelial barrier function, making it a key target for studies related to autoimmune diseases and infections. Research has shown that IL-22R expression is tightly regulated in specific cell types, particularly epithelial cells. The receptor's activation triggers multiple downstream signaling cascades that influence cell survival, proliferation, and antimicrobial defense mechanisms. Understanding IL-22R signaling pathways can reveal potential therapeutic strategies for various inflammatory conditions. Investigating IL-22R interactions with its ligands provides valuable information about immune system regulation and tissue repair processes. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of IL-22R biology and its impact on human health.

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IL-22R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-22Rα1 Antibody (3-RE40)

sc-134366mouse IgG3 κ19-575 (h)WB, IP, ELISAh
3
(5)

IL-22R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-22Rα1 siRNA (h)

sc-88174hGene SilencingN/A0
(0)

IL-22Rα1 shRNA Plasmid (h)

sc-88174-SHhGene SilencingPuromycin0
(0)

IL-22Rα1 shRNA (h) Lentiviral Particles

sc-88174-VhGene SilencingPuromycin0
(0)

IL-22Rα1 siRNA (m)

sc-146217mGene SilencingN/A0
(0)

IL-22Rα1 shRNA Plasmid (m)

sc-146217-SHmGene SilencingPuromycin0
(0)

IL-22Rα1 shRNA (m) Lentiviral Particles

sc-146217-VmGene SilencingPuromycin0
(0)

IL-22Rα2 siRNA (h)

sc-62495hGene SilencingN/A0
(0)

IL-22Rα2 shRNA Plasmid (h)

sc-62495-SHhGene SilencingPuromycin0
(0)

IL-22Rα2 shRNA (h) Lentiviral Particles

sc-62495-VhGene SilencingPuromycin0
(0)

IL-22Rα2 siRNA (m)

sc-62496mGene SilencingN/A0
(0)

IL-22Rα2 shRNA Plasmid (m)

sc-62496-SHmGene SilencingPuromycin0
(0)

IL-22Rα2 shRNA (m) Lentiviral Particles

sc-62496-VmGene SilencingPuromycin0
(0)

IL-22R CRISPR Knockout (KO) and HDR Plasmids

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IL-22Rα1 CRISPR/Cas9 KO Plasmid (h)

sc-404104Gene Knockouth0
(0)

IL-22Rα1 HDR Plasmid (h)

sc-404104-HDRHomology Directed Repairh0
(0)

IL-22Rα1 CRISPR/Cas9 KO Plasmid (m)

sc-433000Gene Knockoutm0
(0)

IL-22Rα1 HDR Plasmid (m)

sc-433000-HDRHomology Directed Repairm0
(0)

IL-22R CRISPR Activation Plasmids and Lentiviral Particles

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IL-22Rα1 CRISPR Activation Plasmid (h)

sc-404104-ACTGene Activationh0
(0)

IL-22Rα2 CRISPR Activation Plasmid (h)

sc-404981-ACTGene Activationh0
(0)