Date published: 2025-10-27

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DDX26B Inhibidores

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

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Nombre del productoNÚMERO DE CAS #Número de catálogoCantidadPrecioMENCIONESClasificación

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

La actinomicina D se une al ADN, inhibiendo la transcripción e impidiendo la síntesis del ARNm DDX26B.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

La cicloheximida interrumpe la síntesis de proteínas, lo que conduce a una reducción de la expresión de DDX26B mediante la inhibición de la traducción.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

La puromicina induce la terminación prematura de la síntesis de proteínas, afectando a la traducción y reduciendo los niveles de DDX26B.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

La rifampicina inhibe la ARN polimerasa bacteriana, suprimiendo indirectamente la expresión de DDX26B al interferir en la transcripción.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

La anisomicina dificulta la síntesis de proteínas al bloquear la actividad de la peptidil transferasa, lo que provoca una reducción de la síntesis de DDX26B.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

La cordicepina interfiere en la síntesis de ARNm, afectando a la transcripción y contribuyendo a la regulación a la baja de DDX26B.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

El ácido micofenólico inhibe la inosina monofosfato deshidrogenasa, afectando indirectamente a la expresión de DDX26B al alterar la síntesis de purinas.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$360.00
$475.00
20
(2)

La blasticidina S induce la terminación prematura durante la traducción, inhibiendo la síntesis de proteínas y reduciendo los niveles de DDX26B.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

El 5-Fluorouracilo interfiere con la síntesis de ARN, afectando a la expresión de DDX26B al interrumpir la producción de ARNm.