Date published: 2026-5-7

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CTLA Antibodies

Santa Cruz Biotechnology features a diverse variety of CTLA Antibodies for research in immunology and cancer biology. CTLA Antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) plays a critical role in regulating immune responses by acting as an inhibitory receptor on T cells. CTLA-4 function is essential for maintaining immune homeostasis and preventing autoimmunity, making it a significant target in cancer immunotherapy. The modulation of CTLA-4 activity has been shown to enhance anti-tumor immunity, highlighting its importance in the development of therapeutic strategies. Researchers can investigate immune checkpoint pathways and their impact on T cell responses using specific monoclonal antibodies. Understanding CTLA-4 signaling mechanisms helps advance knowledge in autoimmune disorders and cancer treatments. Exploring CTLA-4's role in immune regulation continues to reveal new therapeutic possibilities. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of immune checkpoint regulation and contribute to the development of innovative cancer treatments.

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CTLA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CTLA-4 Antibody (F-8)

sc-376016mouse IgG1 κ195-223 (h)WB, IP, IF, IHC(P), ELISAm, r, h
59
(22)

CTLA-4 Antibody (1B8)

sc-18829A. hamster IgGN/AIP, IF, IHC(P), FCMm

new

(2)

CTLA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CTLA-4 CRISPR/Cas9 KO Plasmid (h)

sc-400948hGene KnockoutGFP0
(0)

CTLA-4 HDR Plasmid (h)

sc-400948-HDRhHomology Directed RepairPuromycin0
(0)

CTLA-4 Double Nickase Plasmid (h)

sc-400948-NIChGene KnockoutPuromycin0
(0)

CTLA-4 Double Nickase Plasmid (h2)

sc-400948-NIC-2hGene KnockoutPuromycin0
(0)

CTLA-4 CRISPR/Cas9 KO Plasmid (m)

sc-419533mGene KnockoutGFP0
(0)

CTLA-4 HDR Plasmid (m)

sc-419533-HDRmHomology Directed RepairPuromycin0
(0)

CTLA-4 Double Nickase Plasmid (m)

sc-419533-NICmGene KnockoutPuromycin0
(0)

CTLA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CTLA-4 CRISPR Activation Plasmid (h)

sc-400948-ACThGene ActivationPuro, Blast, Hygro0
(0)

CTLA-4 CRISPR Activation Plasmid (h2)

sc-400948-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CTLA-4 Lentiviral Activation Particles (h)

sc-400948-LAChGene ActivationPuro, Blast, Hygro0
(0)

CTLA-4 Lentiviral Activation Particles (h2)

sc-400948-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CTLA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CTLA-2α siRNA (m)

sc-142619mGene SilencingN/A0
(0)

CTLA-2α shRNA Plasmid (m)

sc-142619-SHmGene SilencingPuromycin0
(0)

CTLA-2α shRNA (m) Lentiviral Particles

sc-142619-VmGene SilencingPuromycin0
(0)

CTLA-4 siRNA (h)

sc-42766hGene SilencingN/A
2
(1)

CTLA-4 shRNA Plasmid (h)

sc-42766-SHhGene SilencingPuromycin
2
(1)

CTLA-4 shRNA (h) Lentiviral Particles

sc-42766-VhGene SilencingPuromycin
2
(1)

CTLA-4 siRNA (m)

sc-42767mGene SilencingN/A0
(1)

CTLA-4 shRNA Plasmid (m)

sc-42767-SHmGene SilencingPuromycin0
(1)

CTLA-4 shRNA (m) Lentiviral Particles

sc-42767-VmGene SilencingPuromycin0
(1)