CASPR2 inhibitors belong to a specialized category of chemical compounds designed to modulate cellular processes associated with the Contactin-associated protein-like 2 (CASPR2) protein. CASPR2, also known as CNTNAP2, is a transmembrane protein primarily expressed in the nervous system, particularly in neurons. It plays a crucial role in the formation and maintenance of neural circuits, influencing synaptic function and neuronal connectivity. The chemical class of CASPR2 inhibitors is characterized by its ability to interact with CASPR2 and interfere with its normal cellular functions.
The molecular structure of CASPR2 inhibitors is designed to selectively target the binding sites or signaling domains of CASPR2, impeding its interactions with other proteins or altering its conformation. By doing so, these inhibitors modulate the downstream signaling cascades associated with CASPR2, potentially affecting synaptic transmission, neuronal migration, and axon guidance. The rationale behind developing CASPR2 inhibitors often stems from the desire to better understand the intricate molecular mechanisms governing neural development and function. Researchers aim to leverage these inhibitors as valuable tools for dissecting the roles of CASPR2 in cellular processes, contributing to a deeper comprehension of neurobiology and potentially unveiling novel insights into the regulation of neural circuits. The chemical class of CASPR2 inhibitors thus serves as a valuable resource for advancing our knowledge of molecular neurobiology, providing researchers with precise means to manipulate CASPR2-mediated processes for experimental exploration and scientific discovery.
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Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
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Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
El litio puede afectar a la señalización de GSK-3β, alterando potencialmente los eventos intracelulares que pueden afectar a CASPR2. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 inhibe NF-κB, que puede influir en las vías de señalización neuronal asociadas con CASPR2. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
El PD98059 inhibe MEK, que forma parte de la vía MAPK/ERK, afectando potencialmente a las interacciones CASPR2. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 inhibe p38 MAPK, y puede influir en las vías de señalización que interactúan con CASPR2 indirectamente. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibe PI3K y puede afectar a las vías de señalización descendentes relacionadas con CASPR2. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
SP600125 inhibe JNK, lo que puede influir en las vías de señalización que modulan indirectamente CASPR2. | ||||||
Casein Kinase I Inhibitor, D4476 | 301836-43-1 | sc-202522 | 1 mg | $97.00 | 6 | |
El D4476 es un inhibidor de la CK1, que puede influir en la señalización Wnt y, por tanto, afectar indirectamente a las funciones de CASPR2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
La rapamicina inhibe mTOR, lo que puede tener efectos secundarios en los procesos celulares en los que interviene CASPR2. | ||||||
Wnt-C59 | 1243243-89-1 | sc-475634 sc-475634A sc-475634B | 5 mg 10 mg 50 mg | $210.00 $320.00 $1250.00 | 1 | |
Wnt-C59 inhibe la producción de Wnt, afectando potencialmente a vías en las que CASPR2 está implicada. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
XAV-939 inhibe la señalización Wnt/β-catenina, lo que puede influir indirectamente en la señalización relacionada con CASPR2. |