Septin 8 Antibody (D-3): sc-390071

Septin 8 Antibody (D-3) is a mouse monoclonal IgG3 antibody that detects Septin 8 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Septin 8 is a 508 amino acid protein that plays a crucial role in various cellular processes, including vesicle trafficking, apoptosis, and cytokinesis, making Septin 8 essential for maintaining cellular integrity and function. Septin 8 is predominantly expressed in the brain, cardiovascular regions, prostate, testis, and ovary, highlighting Septin 8′s significance in both normal physiology and disease states. Notably, Septin 8 interacts with other septins, such as Septin 5, and cell division cycle related-1 (CDCrel-1), suggesting Septin 8′s involvement in complex protein networks that regulate cell division and signaling pathways. Septin 8′s ability to form homo- and hetero-oligomeric polymers that accumulate into higher-order filaments underscores Septin 8′s importance as a dynamic protein scaffold, contributing to cytoskeletal organization and cellular architecture. Furthermore, Septin 8′s association with a-granules in platelets indicates Septin 8′s role in platelet biology, which is vital for hemostasis and wound healing. With diverse functions and interactions, Septin 8 is a key player in various biological processes, making anti-Septin 8 antibody (D-3) an invaluable tool for researchers studying Septin 8′s role in health and disease.

The preferred Septin 8 antibody is Septin 8 Antibody (C-5): sc-390074.