PSA/KLK3/Kallikrein 3/Prostate Specific Antigen Antibody (LT3D2): sc-101384

PSA Antibody (LT3D2) is a mouse monoclonal IgG1 antibody that detects prostate specific antigen (PSA) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Anti-PSA antibody (LT3D2) recognizes PSA, a serine protease primarily produced in the prostate gland, which plays a crucial role in the liquefaction of semen by hydrolyzing semenogelin I, a major protein in seminal plasma. This enzymatic activity is vital for male fertility, as PSA allows sperm to swim freely after ejaculation. Elevated levels of PSA in the blood are often associated with prostate cancer, making PSA an important biomarker for early detection and monitoring of the disease. In addition to PSA′s role in prostate tissues, PSA has also been found in other male reproductive organs and even in breast cancer, highlighting PSA′s significance beyond just prostate health. PSA monoclonal antibody (LT3D2) accurately detects PSA across various applications, making PSA (LT3D2) antibody an essential tool for researchers studying prostate cancer and related conditions.

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PSA/KLK3/Kallikrein 3/Prostate Specific Antigen Antibody (LT3D2) References:

1. Prostate specific antigen gene regulation by androgen receptor.  |  Kim, J. and Coetzee, GA. 2004. J Cell Biochem. 93: 233-41. PMID: 15368351
2. Prostate-specific antigen kinetics in clinical decision-making during active surveillance for early prostate cancer--a review.  |  van den Bergh, RC., et al. 2008. Eur Urol. 54: 505-16. PMID: 18585845
3. Prostate-specific antigen: an evolving role in diagnosis, monitoring, and treatment evaluation in prostate cancer.  |  Payne, H. and Cornford, P. 2011. Urol Oncol. 29: 593-601. PMID: 20060331
4. Next-generation prostate-specific antigen test: precursor form of prostate-specific antigen.  |  Ito, K., et al. 2014. Int J Clin Oncol. 19: 782-92. PMID: 25135462
5. Detection of prostate specific antigen (PSA) in human saliva using an ultra-sensitive nanocomposite of graphene nanoplatelets with diblock-co-polymers and Au electrodes.  |  Khan, MS., et al. 2018. Analyst. 143: 1094-1103. PMID: 29387841
6. Advanced nanoengineered-customized point-of-care tools for prostate-specific antigen.  |  Numan, A., et al. 2021. Mikrochim Acta. 189: 27. PMID: 34905090
7. Blood Prostate-specific Antigen by Volume of Benign, Gleason Pattern 3 and 4 Prostate Tissue.  |  Andolfi, C., et al. 2022. Urology. 170: 154-160. PMID: 35987380
8. Preanalytical stability of molecular forms of prostate-specific antigen in serum samples (PSA, free PSA, [-2]proPSA) and their impact on fPSA/tPSA ratio and PHI.  |  Šimánek, V., et al. 2024. Prostate. 84: 656-665. PMID: 38414098
9. Absolute quantification methods for Prostate-Specific antigen by Isotope-Dilution mass spectrometry.  |  Wu, J., et al. 2024. J Chromatogr B Analyt Technol Biomed Life Sci. 1240: 124112. PMID: 38691944
10. Human Kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate.  |  Rittenhouse, HG., et al. 1998. Crit Rev Clin Lab Sci. 35: 275-368. PMID: 9759557

The preferred PSA/KLK3/Kallikrein 3/Prostate Specific Antigen antibody is PSA/KLK3/Kallikrein 3/Prostate Specific Antigen Antibody (A67-B/E3): sc-7316.