Prolactin Antibody (PRL-149L II): sc-69874
- Prolactin Antibody (PRL-149L II) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against Prolactin of human origin
- recommended for detection of Prolactin of human origin by WB and IP
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Prolactin Antibody (PRL-149L II) for WB applications. These reagents are now offered in bundles with Prolactin Antibody (PRL-149L II) (see ordering information below).
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Prolactin Antibody (PRL-149L II) is a mouse monoclonal IgG1 antibody that detects Prolactin in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Prolactin, a 226 amino acid protein, is primarily secreted by the anterior pituitary gland and plays a crucial role in various physiological processes, including cell growth, reproduction, and immune function. Anti-Prolactin antibody (PRL-149L II) recognizes a protein involved in mammary gland development and lactation, with significance extending to the pathophysiology of mammary cancer, where Prolactin acts as both a mitogen and a differentiating agent. Prolactin enhances the proliferation of B cell hybridomas, which leads to increased antibody production, thereby playing a vital role in the immune response. Prolactin has been shown to counteract the antiproliferative effects of the immunosuppressive cytokine TGF-beta, highlighting its importance in immune regulation. Prolactin is implicated in various autoimmune diseases, including arthritis and type 1 diabetes, making Prolactin monoclonal antibody (PRL-149L II) an essential tool for scientists investigating these conditions in both cancer biology and immunology.
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Prolactin Antibody (PRL-149L II) References:
- Effects of prolactin on hematopoiesis. | Welniak, LA., et al. 2001. Lupus. 10: 700-5. PMID: 11721696
- Prolactin: a pleiotropic neuroendocrine hormone. | Grattan, DR. and Kokay, IC. 2008. J Neuroendocrinol. 20: 752-63. PMID: 18601698
- Prolactin deficiency by aripiprazole. | Lozano, R., et al. 2014. J Clin Psychopharmacol. 34: 539-40. PMID: 24911440
- Prolactin and growth hormone. | Davis, JR., et al. 1988. Baillieres Clin Endocrinol Metab. 2: 797-834. PMID: 3077246
- Prolactin deficiency in pseudohypoparathyroidism. | Carlson, HE., et al. 1977. N Engl J Med. 296: 140-4. PMID: 401530
- Prolactin and male reproduction. | Hermanns, U. and Hafez, ES. 1981. Arch Androl. 6: 95-125. PMID: 6788004
- Physiology of prolactin. | Archer, DF. 1980. Clin Obstet Gynecol. 23: 325-35. PMID: 6994965
- Prolactin in autoimmune diseases. | Neidhart, M. 1998. Proc Soc Exp Biol Med. 217: 408-19. PMID: 9521087
- Prolactin: a hormone at the crossroads of neuroimmunoendocrinology. | Goffin, V., et al. 1998. Ann N Y Acad Sci. 840: 498-509. PMID: 9629276
- Prolactin and human reproduction. | Tolis, G. and Friesen, HG. 1976. Can Med Assoc J. 115: 709-11. PMID: 974957
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prolactin Antibody (PRL-149L II) | sc-69874 | 200 µg/ml | $322.00 | |||
Prolactin Antibody (PRL-149L II): m-IgG Fc BP-HRP Bundle | sc-539251 | 200 µg Ab; 10 µg BP | $361.00 | |||
Prolactin Antibody (PRL-149L II): m-IgG1 BP-HRP Bundle | sc-541356 | 200 µg Ab; 20 µg BP | $361.00 |