Molecular structure of Pipamperone dihydrochloride, CAS Number: 2448-68-2
Pipamperone dihydrochloride (CAS 2448-68-2)
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Alternate Names:
1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamidedihydrochloride
Application:
Pipamperone dihydrochloride is a D2DR and SR-2A inhibitor
CAS Number:
2448-68-2
Molecular Weight:
448.40
Molecular Formula:
C21H30N3O2F•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Pipamperone dihydrochloride is an inhibitor of D2DR and SR-2A. It is a diphenylbutylpiperidine. Pipamperone dihydrochloride can be explored for its role in research studies focused on understanding neurotransmission. Its ability to bind selectively to certain receptors makes it a useful tool in the study of neural pathways and the effects of neurotransmitter imbalances. Additionally, its properties can be applied in the development of models for neuroscientific studies, aiding in the investigation of cognitive processes.
Pipamperone dihydrochloride (CAS 2448-68-2) References
- Different regulation of rat 5-HT(2A) and rat 5-HT(2C) receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone. | Oekelen, DV., et al. 2001. Eur J Pharmacol. 425: 21-32. PMID: 11672571
- Differential-pulse polarography determination of pipamperone in pharmaceutical formulations. | Belgaied, JE. and Trabelsi, H. 2002. J Pharm Biomed Anal. 30: 1417-23. PMID: 12408934
- Stability indicating LC method for the determination of pipamperone. | Trabelsi, H., et al. 2005. J Pharm Biomed Anal. 39: 914-9. PMID: 16040223
- Influence of the antipsychotic drug pipamperone on the expression of the dopamine D4 receptor. | Van Craenenbroeck, K., et al. 2006. Life Sci. 80: 74-81. PMID: 16978659
- Evaluation of serotonin-2A receptor occupancy with 123I-5-I-R91150 and single-photon emission tomography before and after low-dose pipamperone administration in the canine brain. | Peremans, K., et al. 2008. Nucl Med Commun. 29: 724-9. PMID: 18753826
- A field study on 8 pharmaceuticals and 1 pesticide in Belgium: removal rates in waste water treatment plants and occurrence in surface water. | Van De Steene, JC., et al. 2010. Sci Total Environ. 408: 3448-53. PMID: 20471061
- Pipamperone augmentation of clozapine and sodium valproate in refractory schizophrenia: a case report. | Paraschakis, A. 2014. Clin Neuropharmacol. 37: 60-1. PMID: 24614672
- Identification and quantification of the antipsychotics risperidone, aripiprazole, pipamperone and their major metabolites in plasma using ultra-high performance liquid chromatography-mass spectrometry. | Wijma, RA., et al. 2016. Biomed Chromatogr. 30: 794-801. PMID: 26447610
- Quantification of piritramide in human colostrum. | Van Eeckhaut, A., et al. 2017. J Clin Pharm Ther. 42: 306-310. PMID: 28295465
- Dried Blood Spots Combined With Ultra-High-Performance Liquid Chromatography-Mass Spectrometry for the Quantification of the Antipsychotics Risperidone, Aripiprazole, Pipamperone, and Their Major Metabolites. | Tron, C., et al. 2017. Ther Drug Monit. 39: 429-440. PMID: 28700523
- Pipamperone and delirium: a preliminary evaluation of its effectiveness in the management of delirium and its subtypes. | Boettger, S., et al. 2017. Swiss Med Wkly. 147: w14471. PMID: 28750419
- A pan-cancer analysis of the HER family gene and their association with prognosis, tumor microenvironment, and therapeutic targets. | Yang, X., et al. 2021. Life Sci. 273: 119307. PMID: 33691171
- Drug-Associated Liver Injury Related to Antipsychotics: Exploratory Analysis of Pharmacovigilance Data. | Zeiss, R., et al. J Clin Psychopharmacol. 42: 440-444. PMID: 35730552
- A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics. | Guo, Y., et al. 2022. Front Endocrinol (Lausanne). 13: 1058250. PMID: 36686470
Inhibitor of:
D2DR, and SR-2A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pipamperone dihydrochloride, 100 mg | sc-253278 | 100 mg | $233.00 |