PAK6 Antibody (C-2): sc-393102

PAK6 Antibody (C-2) is a mouse monoclonal IgG2a antibody that detects PAK6 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PAK6, a member of the p21(CDKN1A)-activated kinase family, plays a crucial role in various cellular processes, including cell morphology, motility, and apoptosis, by interacting with activated small GTPases like Cdc42 and Rac. PAK6 is involved in the regulation of androgen receptor activity, as PAK6 cotranslocates into the nucleus with this steroid hormone-dependent transcription factor in response to androgen stimulation. This interaction is vital for male sexual differentiation and development, highlighting PAK6′s importance in reproductive biology. PAK6 transcripts show notably high expression in the brain and testis, with lower levels detected in other tissues such as the prostate and breast, indicating specific roles in these organs. The human PAK6 gene is located on chromosome 15q14, further emphasizing PAK6′s significance in human health and disease. Anti-PAK6 antibody (C-2) is an essential tool for researchers investigating the functional dynamics of this important kinase in various biological contexts.

The preferred PAK6 antibody is PAK6 Antibody (H-6): sc-393075.