FGF-2 Antibody (6): sc-136255

FGF-2 Antibody (6) is a mouse monoclonal IgG2a kappa light chain antibody that detects FGF-2 in mouse, rat, human, and canine samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. FGF-2, also known as basic fibroblast growth factor, plays a crucial role in various biological processes, including angiogenesis, wound healing, and tissue repair, making FGF-2 essential for maintaining cellular homeostasis and promoting cell proliferation. FGF-2 is primarily located in the cytoplasm and nucleus of cells, where FGF-2 can exert effects on cell growth and differentiation. The localization of FGF-2 is significant because FGF-2 allows for rapid responses to cellular signals, facilitating a role in developmental processes and repair of damaged tissues. Anti-FGF-2 antibody (6) is available in both conjugated and non-conjugated forms, providing flexibility for various experimental needs, and cross-species recognition enhances utility in comparative studies and translational research.

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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.

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FGF-2 Antibody (6) References:

1. FGF-2-mediated signal transduction during endothelial mesenchymal transformation in corneal endothelial cells.  |  Lee, JG. and Kay, EP. 2006. Exp Eye Res. 83: 1309-16. PMID: 16769055
2. FGF-2 induces neuronal death through upregulation of system xc-.  |  Liu, X., et al. 2014. Brain Res. 1547: 25-33. PMID: 24374066
3. Optimizing BMP-2-induced bone repair with FGF-2.  |  Gronowicz, G., et al. 2014. J Am Acad Orthop Surg. 22: 677-9. PMID: 25281263
4. Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar.  |  Sideek, MA., et al. 2016. J Mol Histol. 47: 35-45. PMID: 26644005
5. FGF-2 Attenuates Neuronal Apoptosis via FGFR3/PI3k/Akt Signaling Pathway After Subarachnoid Hemorrhage.  |  Okada, T., et al. 2019. Mol Neurobiol. 56: 8203-8219. PMID: 31203572
6. Distinct Osteogenic Potentials of BMP-2 and FGF-2 in Extramedullary and Medullary Microenvironments.  |  Nosho, S., et al. 2020. Int J Mol Sci. 21: PMID: 33120952
7. FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells.  |  Jia, T., et al. 2021. BMC Biol. 19: 173. PMID: 34433435
8. The enhancing effects of heparin on the biological activity of FGF-2 in heparin-FGF-2-calcium phosphate composite layers.  |  Yasunaga, M., et al. 2022. Acta Biomater. 148: 345-354. PMID: 35697197
9. Phenol-Grafted Alginate Sulfate Hydrogel as an Injectable FGF-2 Carrier.  |  Goto, R., et al. 2022. Gels. 8: PMID: 36547342
10. Radiolabelled FGF-2 for Imaging Activated Fibroblasts in the Tumor Micro-Environment.  |  Bentivoglio, V., et al. 2024. Biomolecules. 14: PMID: 38672507

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FGF-2 Antibody (6) has 17 citations in a variety of scientific publications.

Primary antibodies like Anti-FGF-2 Antibody (6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FGF-2 Antibody (6) Specifications

Alternate Product Name: FGF2

Product Clone Name: 6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-155

Epitope Target: FGF-2

Epitope Species: human

Product Reactivity/Detection: FGF-2

Species Reactivity/Detection: mouse, rat, human, canine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 17 citations in various scientific publications

Available Conjugates/Forms for FGF-2 Antibody (6): AC: Agarose, HRP: Horseradish Peroxidase

The preferred FGF-2 antibody is FGF-2 Antibody (C-2): sc-74412.