Date published: 2026-6-3

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Unc18 Antibodies

Santa Cruz Biotechnology offers a broad range of Unc18 monoclonal antibodies for advanced research in neuroscience and cellular signaling. Unc18 Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Unc18, also known as Munc18, plays a critical role in synaptic transmission by regulating the docking and fusion of synaptic vesicles with the presynaptic membrane. Unc18 is essential for neurotransmitter release, making it a key player in neuronal communication and overall brain function. Understanding the mechanisms involving Unc18 is crucial for elucidating various neurological disorders and developing potential therapeutic strategies. Researchers worldwide rely on Unc18 monoclonal antibodies to investigate synaptic vesicle regulation and neurotransmitter release mechanisms. Advanced research techniques using Unc18 monoclonal antibodies have revealed important insights into neurological conditions and potential treatment approaches. The specificity and reliability of Santa Cruz Biotechnology monoclonal antibodies enable researchers to make meaningful contributions to neuroscience research and advance our understanding of neurological disorders.

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Unc18 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Unc18-1 Antibody (31)

sc-136304mouse IgG1381-567 (r)WB, IP, IF, IHC(P)m, r, h
1
(2)

Unc18-1/2 Antibody (D-1)

sc-133169mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(3)

Unc18-2 Antibody (B-2)

sc-376639mouse IgM κ481-519 (h)WB, IP, IF, ELISAm, r, h

new

(4)

Unc18-2 Antibody (A-6)

sc-390503mouse IgG1 κ477-516 (h)WB, IP, IF, ELISAm, r, h
1
(3)

Unc18-2 Antibody (D-2)

sc-390864mouse IgG2a κ477-516 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Unc18-3 Antibody (H-7)

sc-373813mouse IgG1 κ501-533 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

Unc18 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Unc18-1 CRISPR/Cas9 KO Plasmid (m)

sc-423210mGene KnockoutGFP0
(0)

Unc18-1 HDR Plasmid (m)

sc-423210-HDRmHomology Directed RepairPuromycin0
(0)

Unc18-2 CRISPR/Cas9 KO Plasmid (h)

sc-403691hGene KnockoutGFP0
(0)

Unc18-2 HDR Plasmid (h)

sc-403691-HDRhHomology Directed RepairPuromycin0
(0)

Unc18-2 CRISPR/Cas9 KO Plasmid (r)

sc-437364rGene KnockoutGFP0
(0)

Unc18-2 HDR Plasmid (r)

sc-437364-HDRrHomology Directed RepairPuromycin0
(0)

Unc18 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Unc18-1 CRISPR Activation Plasmid (h)

sc-403761-ACThGene ActivationPuro, Blast, Hygro0
(0)

Unc18-2 CRISPR Activation Plasmid (h)

sc-403691-ACThGene ActivationPuro, Blast, Hygro0
(0)

Unc18 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Unc18-1 siRNA (h)

sc-42308hGene SilencingN/A0
(0)

Unc18-1 shRNA Plasmid (h)

sc-42308-SHhGene SilencingPuromycin0
(0)

Unc18-1 shRNA (h) Lentiviral Particles

sc-42308-VhGene SilencingPuromycin0
(0)

Unc18-1 siRNA (m)

sc-42309mGene SilencingN/A0
(0)

Unc18-1 shRNA Plasmid (m)

sc-42309-SHmGene SilencingPuromycin0
(0)

Unc18-1 shRNA (m) Lentiviral Particles

sc-42309-VmGene SilencingPuromycin0
(0)

Unc18-1 siRNA (r)

sc-270657rGene SilencingN/A0
(0)

Unc18-1 shRNA Plasmid (r)

sc-270657-SHrGene SilencingPuromycin0
(0)

Unc18-1 shRNA (r) Lentiviral Particles

sc-270657-VrGene SilencingPuromycin0
(0)

Unc18-1 (r)-PR

sc-270657-PRrPrimerN/A0
(0)

Unc18-2 siRNA (h)

sc-42310hGene SilencingN/A0
(0)

Unc18-2 shRNA Plasmid (h)

sc-42310-SHhGene SilencingPuromycin0
(0)

Unc18-2 shRNA (h) Lentiviral Particles

sc-42310-VhGene SilencingPuromycin0
(0)

Unc18-2 siRNA (m)

sc-42311mGene SilencingN/A0
(0)

Unc18-2 shRNA Plasmid (m)

sc-42311-SHmGene SilencingPuromycin0
(0)

Unc18-2 shRNA (m) Lentiviral Particles

sc-42311-VmGene SilencingPuromycin0
(0)

Unc18-3 siRNA (h)

sc-42312hGene SilencingN/A
1
(0)

Unc18-3 shRNA Plasmid (h)

sc-42312-SHhGene SilencingPuromycin
1
(0)

Unc18-3 shRNA (h) Lentiviral Particles

sc-42312-VhGene SilencingPuromycin
1
(0)

Unc18-3 siRNA (m)

sc-42313mGene SilencingN/A0
(0)

Unc18-3 shRNA Plasmid (m)

sc-42313-SHmGene SilencingPuromycin0
(0)

Unc18-3 shRNA (m) Lentiviral Particles

sc-42313-VmGene SilencingPuromycin0
(0)