Date published: 2025-9-9

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SMC Antikörper und Ähnliche Produkte

Santa Cruz Biotechnology bietet eine umfassende Sammlung von SMC-Antikörpern zur Untersuchung der strukturellen Erhaltung von Chromosomenproteinen. SMC-Antikörper sind mit einer Vielzahl von Forschungsanwendungen kompatibel, darunter Western Blotting (WB), Immunpräzipitation (IP), Immunfluoreszenz (IF), Immunhistochemie mit Paraffin eingebetteten Schnitten (IHCP), Durchflusszytometrie (FCM) und Enzyme-Linked Immunosorbent Assay (ELISA). SMC-Proteine spielen eine wichtige Rolle bei der Chromosomenorganisation, der Segregation und der DNA-Reparatur, wodurch die genomische Stabilität während der Zellteilung aufrechterhalten wird. Eine ordnungsgemäße Funktion der SMC-Proteine verhindert Chromosomenanomalien, die zu verschiedenen Krankheiten, einschließlich Krebs, führen können. Das Verständnis der Dynamik von SMC-Proteinen bietet Einblicke in grundlegende zelluläre Prozesse und potenzielle therapeutische Ziele. Die Forschung auf dem Gebiet der Chromosomenbiologie hat gezeigt, dass SMC-Proteine eine Schlüsselrolle bei der Erhaltung des Genoms und dem Fortschreiten des Zellzyklus spielen. Die Erforschung der Mechanismen von SMC-Proteinen trägt dazu bei, neue Ansätze für die Behandlung von Chromosomenstörungen und Entwicklungsanomalien zu finden. Aktuelle Studien konzentrieren sich auf die Frage, wie SMC-Proteine mit anderen zellulären Faktoren koordiniert werden, um eine genaue DNA-Verteilung während der Mitose und Meiose zu gewährleisten. Die monoklonalen Antikörper von Santa Cruz Biotechnology ermöglichen es Forschern weltweit, das wissenschaftliche Verständnis der Chromosomenbiologie zu verbessern und zu bahnbrechenden Entdeckungen in der Zellteilungsforschung beizutragen.

Siehe auch...

SMC Antikörper

Empty Table HeaderProduktKatnr.IsotypEpitopAnwendungenSpeciesReferenzenBewertung

SMC1 Antikörper (C2M)

sc-56776mouse IgG1 κ402-894 (h)WB, IPh
1
(4)

SMC1α Antikörper (H-6)

sc-393171mouse IgG3 κ1202-1233 (h)WB, IP, IF, ELISAm, r, h
3
(2)

SMC1α Antikörper (E-8)

sc-166734mouse IgM κInternal (h)WB, IP, IF, ELISAm, r, h

neu

(1)

SMC3 Antikörper (E-3)

sc-376352mouse IgG1 κ811-1110 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(7)

SMC3 Antikörper (A-7)

sc-365540mouse IgG3 κ1163-1188 (r)WB, IP, IF, ELISAm, r, h

neu

(1)

SMC5 Antikörper (B-11)

sc-393282mouse IgG2a κ901-1090 (h)WB, IP, IF, ELISAm, r, h
3
(2)

SMC6 Antikörper (A-3)

sc-365742mouse IgG1 κ845-1072 (h)WB, IP, IF, ELISAm, r, h
6
(3)

SMC6 Antikörper (C-4)

sc-515163mouse IgG2a κ975-997 (h)WB, IP, IF, ELISAh

neu

(0)

Phospho-Spezifische SMC Antikörper

Empty Table HeaderProduktKatnr.IsotypEpitopAnwendungenSpeciesReferenzenBewertung

p-SMC1 Antikörper (5D11G5)

sc-56746mouse IgG1 κSer 957 (h)WB, IP, IF, IHC(P)m, r, h

neu

(2)

p-SMC1 Antikörper (4H374)

sc-71790mouse IgG1 κSer 957 (h)WB, IP, IFm, r, h

neu

(1)

p-SMC1 Antikörper (5H24)

sc-71789mouse IgG1 κSer 957 (h)WB, IP, IFm, r, h

neu

(1)

p-SMC1α Antikörper (43.Ser 966)

sc-135784mouse IgG2b κSer 966 (m)WB, IP, ELISAm, r, h

neu

(1)

SMC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

SMC1 CRISPR/Cas9 KO Plasmid (h)

sc-403715hGene KnockoutGFP0
(0)

SMC1 HDR Plasmid (h)

sc-403715-HDRhHomology Directed RepairPuromycin0
(0)

SMC1 Double Nickase Plasmid (h)

sc-403715-NIChGene KnockoutPuromycin0
(0)

SMC1 Double Nickase Plasmid (h2)

sc-403715-NIC-2hGene KnockoutPuromycin0
(0)

SMC1α CRISPR/Cas9 KO Plasmid (h)

sc-402865hGene KnockoutGFP0
(0)

SMC1α HDR Plasmid (h)

sc-402865-HDRhHomology Directed RepairPuromycin0
(0)

SMC1α Double Nickase Plasmid (h)

sc-402865-NIChGene KnockoutPuromycin0
(0)

SMC1α Double Nickase Plasmid (h2)

sc-402865-NIC-2hGene KnockoutPuromycin0
(0)

SMC1α CRISPR/Cas9 KO Plasmid (m)

sc-423967mGene KnockoutGFP0
(0)

SMC1α HDR Plasmid (m)

sc-423967-HDRmHomology Directed RepairPuromycin0
(0)

SMC1α Double Nickase Plasmid (m)

sc-423967-NICmGene KnockoutPuromycin0
(0)

SMC1α Double Nickase Plasmid (m2)

sc-423967-NIC-2mGene KnockoutPuromycin0
(0)

SMC1β CRISPR/Cas9 KO Plasmid (m)

sc-431224mGene KnockoutGFP0
(0)

SMC1β HDR Plasmid (m)

sc-431224-HDRmHomology Directed RepairPuromycin0
(0)

SMC1β Double Nickase Plasmid (m)

sc-431224-NICmGene KnockoutPuromycin0
(0)

SMC1β Double Nickase Plasmid (m2)

sc-431224-NIC-2mGene KnockoutPuromycin0
(0)

SMC2 CRISPR/Cas9 KO Plasmid (h)

sc-411488hGene KnockoutGFP0
(0)

SMC2 HDR Plasmid (h)

sc-411488-HDRhHomology Directed RepairPuromycin0
(0)

SMC2 Double Nickase Plasmid (h)

sc-411488-NIChGene KnockoutPuromycin0
(0)

SMC2 Double Nickase Plasmid (h2)

sc-411488-NIC-2hGene KnockoutPuromycin0
(0)

SMC2 CRISPR/Cas9 KO Plasmid (m)

sc-420357mGene KnockoutGFP0
(0)

SMC2 HDR Plasmid (m)

sc-420357-HDRmHomology Directed RepairPuromycin0
(0)

SMC2 Double Nickase Plasmid (m)

sc-420357-NICmGene KnockoutPuromycin0
(0)

SMC2 Double Nickase Plasmid (m2)

sc-420357-NIC-2mGene KnockoutPuromycin0
(0)

SMC3 CRISPR/Cas9 KO Plasmid (h)

sc-403950hGene KnockoutGFP0
(0)

SMC3 HDR Plasmid (h)

sc-403950-HDRhHomology Directed RepairPuromycin0
(0)

SMC3 Double Nickase Plasmid (h)

sc-403950-NIChGene KnockoutPuromycin0
(0)

SMC3 Double Nickase Plasmid (h2)

sc-403950-NIC-2hGene KnockoutPuromycin0
(0)

SMC3 CRISPR/Cas9 KO Plasmid (m)

sc-419858mGene KnockoutGFP0
(0)

SMC3 HDR Plasmid (m)

sc-419858-HDRmHomology Directed RepairPuromycin0
(0)

SMC3 Double Nickase Plasmid (m)

sc-419858-NICmGene KnockoutPuromycin0
(0)

SMC3 Double Nickase Plasmid (m2)

sc-419858-NIC-2mGene KnockoutPuromycin0
(0)

SMC4 CRISPR/Cas9 KO Plasmid (h)

sc-405067hGene KnockoutGFP0
(0)

SMC4 HDR Plasmid (h)

sc-405067-HDRhHomology Directed RepairPuromycin0
(0)

SMC4 Double Nickase Plasmid (h)

sc-405067-NIChGene KnockoutPuromycin0
(0)

SMC4 Double Nickase Plasmid (h2)

sc-405067-NIC-2hGene KnockoutPuromycin0
(0)

SMC4 CRISPR/Cas9 KO Plasmid (m)

sc-427620mGene KnockoutGFP0
(0)

SMC4 HDR Plasmid (m)

sc-427620-HDRmHomology Directed RepairPuromycin0
(0)

SMC4 Double Nickase Plasmid (m)

sc-427620-NICmGene KnockoutPuromycin0
(0)

SMC4 Double Nickase Plasmid (m2)

sc-427620-NIC-2mGene KnockoutPuromycin0
(0)

SMC5 CRISPR/Cas9 KO Plasmid (h)

sc-405958hGene KnockoutGFP0
(0)

SMC5 HDR Plasmid (h)

sc-405958-HDRhHomology Directed RepairPuromycin0
(0)

SMC5 Double Nickase Plasmid (h)

sc-405958-NIChGene KnockoutPuromycin0
(0)

SMC5 Double Nickase Plasmid (h2)

sc-405958-NIC-2hGene KnockoutPuromycin0
(0)

SMC5 CRISPR/Cas9 KO Plasmid (m)

sc-432584mGene KnockoutGFP0
(0)

SMC5 HDR Plasmid (m)

sc-432584-HDRmHomology Directed RepairPuromycin0
(0)

SMC5 Double Nickase Plasmid (m)

sc-432584-NICmGene KnockoutPuromycin0
(0)

SMC5 Double Nickase Plasmid (m2)

sc-432584-NIC-2mGene KnockoutPuromycin0
(0)

SMC6 CRISPR/Cas9 KO Plasmid (h)

sc-402805hGene KnockoutGFP0
(0)

SMC6 HDR Plasmid (h)

sc-402805-HDRhHomology Directed RepairPuromycin0
(0)

SMC6 Double Nickase Plasmid (h)

sc-402805-NIChGene KnockoutPuromycin0
(0)

SMC6 Double Nickase Plasmid (h2)

sc-402805-NIC-2hGene KnockoutPuromycin0
(0)

SMC6 CRISPR/Cas9 KO Plasmid (m)

sc-426462mGene KnockoutGFP0
(0)

SMC6 HDR Plasmid (m)

sc-426462-HDRmHomology Directed RepairPuromycin0
(0)

SMC6 Double Nickase Plasmid (m)

sc-426462-NICmGene KnockoutPuromycin0
(0)

SMC6 Double Nickase Plasmid (m2)

sc-426462-NIC-2mGene KnockoutPuromycin0
(0)

SMC CRISPR Activation Products

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

SMC1 CRISPR Activation Plasmid (h)

sc-403715-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC1 CRISPR Activation Plasmid (h2)

sc-403715-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC1 Lentiviral Activation Particles (h)

sc-403715-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC1 Lentiviral Activation Particles (h2)

sc-403715-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (h)

sc-402865-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (h2)

sc-402865-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC1α Lentiviral Activation Particles (h)

sc-402865-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC1α Lentiviral Activation Particles (h2)

sc-402865-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (m)

sc-423967-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (m2)

sc-423967-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC1α Lentiviral Activation Particles (m)

sc-423967-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC1α Lentiviral Activation Particles (m2)

sc-423967-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC1β CRISPR Activation Plasmid (m)

sc-431224-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC1β CRISPR Activation Plasmid (m2)

sc-431224-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC1β Lentiviral Activation Particles (m)

sc-431224-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC1β Lentiviral Activation Particles (m2)

sc-431224-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC2 CRISPR Activation Plasmid (h)

sc-411488-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC2 CRISPR Activation Plasmid (h2)

sc-411488-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC2 Lentiviral Activation Particles (h)

sc-411488-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC2 Lentiviral Activation Particles (h2)

sc-411488-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC2 CRISPR Activation Plasmid (m)

sc-420357-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC2 CRISPR Activation Plasmid (m2)

sc-420357-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC2 Lentiviral Activation Particles (m)

sc-420357-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC2 Lentiviral Activation Particles (m2)

sc-420357-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC3 CRISPR Activation Plasmid (h)

sc-403950-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC3 CRISPR Activation Plasmid (h2)

sc-403950-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC3 Lentiviral Activation Particles (h)

sc-403950-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC3 Lentiviral Activation Particles (h2)

sc-403950-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC3 CRISPR Activation Plasmid (m)

sc-419858-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC3 CRISPR Activation Plasmid (m2)

sc-419858-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC3 Lentiviral Activation Particles (m)

sc-419858-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC3 Lentiviral Activation Particles (m2)

sc-419858-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC4 CRISPR Activation Plasmid (h)

sc-405067-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC4 CRISPR Activation Plasmid (h2)

sc-405067-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC4 Lentiviral Activation Particles (h)

sc-405067-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC4 Lentiviral Activation Particles (h2)

sc-405067-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC4 CRISPR Activation Plasmid (m)

sc-427620-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC4 CRISPR Activation Plasmid (m2)

sc-427620-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC4 Lentiviral Activation Particles (m)

sc-427620-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC4 Lentiviral Activation Particles (m2)

sc-427620-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC5 CRISPR Activation Plasmid (h)

sc-405958-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC5 CRISPR Activation Plasmid (h2)

sc-405958-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC5 Lentiviral Activation Particles (h)

sc-405958-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC5 Lentiviral Activation Particles (h2)

sc-405958-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC5 CRISPR Activation Plasmid (m)

sc-432584-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC5 CRISPR Activation Plasmid (m2)

sc-432584-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC5 Lentiviral Activation Particles (m)

sc-432584-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC5 Lentiviral Activation Particles (m2)

sc-432584-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (h)

sc-402805-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (h2)

sc-402805-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC6 Lentiviral Activation Particles (h)

sc-402805-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMC6 Lentiviral Activation Particles (h2)

sc-402805-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (m)

sc-426462-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (m2)

sc-426462-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC6 Lentiviral Activation Particles (m)

sc-426462-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMC6 Lentiviral Activation Particles (m2)

sc-426462-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

SMC1 siRNA (h)

sc-63348hGene SilencingN/A0
(0)

SMC1α siRNA (h)

sc-38385hGene SilencingN/A0
(0)

SMC1α siRNA (h2)

sc-38387hGene SilencingN/A0
(0)

SMC1α shRNA Plasmid (h)

sc-38385-SHhGene SilencingPuromycin0
(0)

SMC1α shRNA Plasmid (h2)

sc-38387-SHhGene SilencingPuromycin0
(0)

SMC1α shRNA (h) Lentivirale Partikel

sc-38385-VhGene SilencingPuromycin0
(0)

SMC1α shRNA (h2) Lentivirale Partikel

sc-38387-VhGene SilencingPuromycin0
(0)

SMC1α siRNA (m)

sc-38386mGene SilencingN/A0
(0)

SMC1α shRNA Plasmid (m)

sc-38386-SHmGene SilencingPuromycin0
(0)

SMC1α shRNA (m) Lentivirale Partikel

sc-38386-VmGene SilencingPuromycin0
(0)

SMC1β shRNA Plasmid (h)

sc-63348-SHhGene SilencingPuromycin0
(0)

SMC1β shRNA (h) Lentivirale Partikel

sc-63348-VhGene SilencingPuromycin0
(0)

SMC1β siRNA (m)

sc-38388mGene SilencingN/A0
(0)

SMC1β shRNA Plasmid (m)

sc-38388-SHmGene SilencingPuromycin0
(0)

SMC1β shRNA (m) Lentivirale Partikel

sc-38388-VmGene SilencingPuromycin0
(0)

SMC2 siRNA (h)

sc-38389hGene SilencingN/A0
(0)

SMC2 shRNA Plasmid (h)

sc-38389-SHhGene SilencingPuromycin0
(0)

SMC2 shRNA (h) Lentivirale Partikel

sc-38389-VhGene SilencingPuromycin0
(0)

SMC2 siRNA (m)

sc-38390mGene SilencingN/A0
(0)

SMC2 shRNA Plasmid (m)

sc-38390-SHmGene SilencingPuromycin0
(0)

SMC2 shRNA (m) Lentivirale Partikel

sc-38390-VmGene SilencingPuromycin0
(0)

SMC3 siRNA (h)

sc-38391hGene SilencingN/A0
(0)

SMC3 shRNA Plasmid (h)

sc-38391-SHhGene SilencingPuromycin0
(0)

SMC3 shRNA (h) Lentivirale Partikel

sc-38391-VhGene SilencingPuromycin0
(0)

SMC3 siRNA (m)

sc-38392mGene SilencingN/A0
(0)

SMC3 shRNA Plasmid (m)

sc-38392-SHmGene SilencingPuromycin0
(0)

SMC3 shRNA (m) Lentivirale Partikel

sc-38392-VmGene SilencingPuromycin0
(0)

SMC4 siRNA (h)

sc-38384hGene SilencingN/A0
(0)

SMC4 shRNA Plasmid (h)

sc-38384-SHhGene SilencingPuromycin0
(0)

SMC4 shRNA (h) Lentivirale Partikel

sc-38384-VhGene SilencingPuromycin0
(0)

SMC4 siRNA (m)

sc-153620mGene SilencingN/A0
(0)

SMC4 shRNA Plasmid (m)

sc-153620-SHmGene SilencingPuromycin0
(0)

SMC4 shRNA (m) Lentivirale Partikel

sc-153620-VmGene SilencingPuromycin0
(0)

SMC5 siRNA (h)

sc-61563hGene SilencingN/A0
(0)

SMC5 shRNA Plasmid (h)

sc-61563-SHhGene SilencingPuromycin0
(0)

SMC5 shRNA (h) Lentivirale Partikel

sc-61563-VhGene SilencingPuromycin0
(0)

SMC5 siRNA (m)

sc-61564mGene SilencingN/A0
(0)

SMC5 shRNA Plasmid (m)

sc-61564-SHmGene SilencingPuromycin0
(0)

SMC5 shRNA (m) Lentivirale Partikel

sc-61564-VmGene SilencingPuromycin0
(0)

SMC6 siRNA (h)

sc-61565hGene SilencingN/A0
(0)

SMC6 shRNA Plasmid (h)

sc-61565-SHhGene SilencingPuromycin0
(0)

SMC6 shRNA (h) Lentivirale Partikel

sc-61565-VhGene SilencingPuromycin0
(0)

SMC6 siRNA (m)

sc-61566mGene SilencingN/A0
(0)

SMC6 shRNA Plasmid (m)

sc-61566-SHmGene SilencingPuromycin0
(0)

SMC6 shRNA (m) Lentivirale Partikel

sc-61566-VmGene SilencingPuromycin0
(0)