Santa Cruz Biotechnology offers conjugated and unconjugated monoclonal primary antibodies directed against most kinases and phosphatases. The phosphorylation state of a molecule may affect its enzymatic activity, localization, interaction and structure. Each of these potential effects may have a profound impact on cell activity and viability. Kinases phosphorylate specific substrates, while phosphatases remove phosphate groups, together controlling target molecule activity.
Most of our popular antibodies are also available as ImmunoCruz® Conjugates, including AC, HRP, PE, FITC, Alexa Fluor® 488, 546, 594, 647, 680, and 790 conjugates for direct Western Blotting and Staining applications, eliminating the need for a secondary antibody. Additional conjugates are also available for many antibodies, including Biotin, TRITC, PE-Cy5, PE-Cy7, APC, APC-Cy7, Alexa Fluor® 405, PerCP and PerCP-Cy5.5.