Date published: 2025-11-17

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Choline bitartrate (CAS 87-67-2)

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Alternate Names:
2-(Hydroxyethyl)trimethylammonium bitartrate
Application:
Choline bitartrate is an acyl group acceptor and a substrate of Choactase
CAS Number:
87-67-2
Molecular Weight:
253.25
Molecular Formula:
C9H19NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Choline bitartrate is a water-soluble compound found in certain foods. It plays a role in various biological processes, including the synthesis of the neurotransmitter acetylcholine, which is involved in muscle control, memory, and other cognitive functions. Choline bitartrate is a nutrient that is important for maintaining the structural integrity of cell membranes and is involved in lipid metabolism. It is a precursor for the synthesis of the methyl donor betaine, which is important for the regulation of gene expression and protein function.


Choline bitartrate (CAS 87-67-2) References

  1. Occurrence, co-occurrence and topographic distribution of choline acetyl transferase, Met-enkephalin and neurotensin in the stellate ganglion of the cat.  |  Jiménez, B., et al. 2002. Synapse. 43: 163-74. PMID: 11793421
  2. Dietary L-methionine supplementation mitigates gamma-radiation induced global DNA hypomethylation: enhanced metabolic flux towards S-adenosyl-L-methionine (SAM) biosynthesis increases genomic methylation potential.  |  Batra, V. and Verma, P. 2014. Food Chem Toxicol. 69: 46-54. PMID: 24721433
  3. Protective effects and mechanisms of total alkaloids of Rubus alceaefolius Poir on non‑alcoholic fatty liver disease in rats.  |  Zheng, H., et al. 2014. Mol Med Rep. 10: 1758-64. PMID: 25051256
  4. Comparative angioprotective effects of magnesium compounds.  |  Kharitonova, M., et al. 2015. J Trace Elem Med Biol. 29: 227-34. PMID: 25127069
  5. Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet.  |  Tanaka, N., et al. 2014. Biochim Biophys Acta. 1841: 1596-607. PMID: 25178843
  6. Dietary ribonucleic acid suppresses inflammation of adipose tissue and improves glucose intolerance that is mediated by immune cells in C57BL/6 mice fed a high-fat diet.  |  Sakai, T., et al. 2015. J Nutr Sci Vitaminol (Tokyo). 61: 73-8. PMID: 25994141
  7. Modified extrusion-spheronization as a technique of microencapsulation for stabilization of choline bitartrate using hydrogenated soya bean oil.  |  Gangurde, AB., et al. 2015. Int J Pharm Investig. 5: 275-83. PMID: 26682198
  8. Choline and betaine ameliorate liver lipid accumulation induced by vitamin B6 deficiency in rats.  |  Kitagawa, E., et al. 2017. Biosci Biotechnol Biochem. 81: 316-322. PMID: 27696964
  9. Chronic choline supplementation improves cognitive and motor performance via modulating oxidative and neurochemical status in rats.  |  Tabassum, S., et al. 2017. Pharmacol Biochem Behav. 159: 90-99. PMID: 28642069
  10. High Choline Intake during Pregnancy Reduces Characteristics of the Metabolic Syndrome in Male Wistar Rat Offspring Fed a High Fat But Not a Normal Fat Post-Weaning Diet.  |  Hammoud, R., et al. 2021. Nutrients. 13: PMID: 33923230
  11. The anion of choline-based ionic liquids tailored interactions between ionic liquids and bovine serum albumin, MCF-7 cells, and bacteria.  |  Wang, X., et al. 2021. Colloids Surf B Biointerfaces. 206: 111971. PMID: 34271329
  12. Dexpanthenol with choline bitartrate in the treatment of infantile colic.  |  Beauregard, WG. 1968. J La State Med Soc. 120: 142-5. PMID: 5648853
  13. Nicotinamide megadosing increases hepatic poly(ADP-ribose) levels in choline-deficient rats.  |  ApSimon, MM., et al. 1995. J Nutr. 125: 1826-32. PMID: 7616297

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Choline bitartrate, 250 g

sc-252599
250 g
$44.00