Date published: 2025-12-18

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Zyxin Activators

MYH11 activators belong to a distinct chemical class known for their ability to modulate the activity of the MYH11 gene. MYH11, short for "myosin heavy chain 11," is a crucial protein involved in the contraction of smooth muscle cells. Smooth muscles are found in various organs and tissues throughout the body, including the blood vessels, airways, and gastrointestinal tract. The MYH11 gene encodes a myosin protein specifically expressed in smooth muscle cells, and its activation plays a fundamental role in regulating smooth muscle contraction. MYH11 activators, therefore, are compounds or molecules that exert an influence on MYH11 expression or function, ultimately impacting the contractility of smooth muscles.

The exact mechanisms through which MYH11 activators operate can vary, but they typically act at the molecular level. Some MYH11 activators may enhance the transcription or expression of the MYH11 gene, leading to increased production of the MYH11 protein. Others may directly interact with the MYH11 protein, altering its conformation or function to promote smooth muscle contraction. These activators can be of significant interest in scientific research and may have potential applications in understanding various physiological processes, such as vascular tone regulation, airway constriction, and gastrointestinal motility. Additionally, studying MYH11 activators can help elucidate the intricate signaling pathways and molecular events involved in smooth muscle function, contributing to a broader understanding of cellular biology and potentially paving the way for future developments in related fields.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA is a potent activator of protein kinase C (PKC), which can activate various signaling pathways. PKC activation can influence cellular processes, potentially affecting Zyxin's role in cytoskeletal organization and cell adhesion.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Y-27632 is a Rho kinase (ROCK) inhibitor. By inhibiting ROCK, it can indirectly affect Zyxin by modulating the RhoA-ROCK pathway, which is involved in cytoskeletal dynamics and cell adhesion.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a broad-spectrum protein kinase inhibitor. It can modulate various signaling pathways, indirectly impacting Zyxin activity by affecting downstream signaling cascades.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A is a histone deacetylase (HDAC) inhibitor. It can affect gene expression and potentially indirectly influence Zyxin by modulating the transcription of related genes.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Paclitaxel is a microtubule stabilizer. By stabilizing microtubules, it indirectly affects Zyxin-related processes associated with cytoskeletal dynamics and cell morphology.

Calpeptin

117591-20-5sc-202516
sc-202516A
10 mg
50 mg
$119.00
$447.00
28
(1)

Calpeptin is a calpain inhibitor. Calpains are calcium-dependent proteases that can cleave Zyxin. Inhibiting calpain activity may indirectly maintain Zyxin levels.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K (Phosphoinositide 3-kinase) inhibitor. By inhibiting PI3K, it can modulate downstream signaling pathways, potentially impacting Zyxin-associated cellular functions.

EHT 1864

754240-09-0sc-361175
sc-361175A
10 mg
50 mg
$209.00
$872.00
12
(2)

EHT 1864 is a Rac1 inhibitor. By inhibiting Rac1, it can affect actin dynamics and cell motility, indirectly influencing Zyxin activity.