Date published: 2025-9-15

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ZNF563 Activators

Compounds like Zinc Chloride directly contribute to the structural integrity of ZNF563, enhancing its DNA-binding capability and thus increasing its regulatory function in gene transcription. Trichostatin A and Sodium Butyrate can alter chromatin structure, thereby impacting ZNF563's role in gene expression regulation. Similarly, 5-Azacytidine, by affecting DNA methylation patterns, can influence the binding and regulatory functions of ZNF563.

Furthermore, compounds targeting various signaling pathways such as Genistein, LY294002, PD98059, and SP600125, through their actions on tyrosine kinase signaling, PI3K/Akt, MAPK/ERK, and JNK pathways respectively, can indirectly impact the cellular context in which ZNF563 operates. This includes its involvement in processes like signal transduction, proliferation, and stress responses. Additionally, Resveratrol, Curcumin, SB431542, and Rapamycin, by modulating sirtuin activity, multiple signaling pathways, TGF-β signaling, and mTOR inhibition, respectively, could indirectly influence the role of ZNF563 in the cellular environment, particularly in pathways related to inflammation, oxidative stress, and cell growth.

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