Date published: 2026-1-11

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ZNF279 Inhibitors

ZNF279, or Zinc Finger Protein 279, belongs to the family of zinc finger proteins, which are characterized by their zinc finger motifs-small, functional domains that stabilize the protein structure through coordination with a zinc ion. These motifs enable zinc finger proteins to interact with other molecules, particularly DNA, RNA, and other proteins, thus allowing them to function as transcription factors, which regulate the expression of genes, or as components in various other cellular processes including DNA recognition, RNA packaging, transcriptional activation, regulation of apoptosis, protein folding and assembly, and lipid binding.The specific structure of ZNF279 comprises multiple zinc finger motifs, which suggests that it may bind to DNA and possibly regulate the transcription of certain genes. Like other zinc finger proteins, ZNF279 is likely involved in transcriptional regulation, but the exact genes it targets and the biological processes it influences can be highly variable and context-dependent.

Research into the functions of ZNF279 is not as extensive as for some other proteins, and much of its role within the cell remains to be elucidated. However, owing to the general functions of zinc finger proteins, ZNF279 may be implicated in the regulation of gene expression, development, differentiation, and possibly the maintenance of genomic integrity.Mutations or dysregulation of zinc finger proteins can be associated with a variety of diseases, including cancer, developmental disorders, and neurological conditions. Therefore, understanding the function of ZNF279, its target genes, and its role in cellular processes could be important for uncovering its potential impact on human health and disease.While specific details on ZNF279 are limited, continued research may reveal its precise mechanisms of action, regulatory targets, and involvement in cellular signaling pathways, contributing to the broader understanding of zinc finger protein functions.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine incorporates into DNA and RNA, leading to hypomethylation of DNA and potentially decreasing ZNF279 gene expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

RG108 is a non-nucleoside DNA methyltransferase inhibitor that can lead to demethylation and may downregulate ZNF279 expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Decitabine is a cytidine analog that targets DNA methylation and could reduce ZNF279 expression by altering methylation patterns.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

Mithramycin A binds to GC-rich DNA sequences, potentially inhibiting the transcription of ZNF279 by blocking its promoter region.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine intercalates into DNA, which may disrupt transcription factor binding and decrease ZNF279 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide has been shown to inhibit the transcription of various genes, which may include ZNF279 through general transcriptional repression.

Fostriecin

87860-39-7sc-202160
50 µg
$265.00
9
(1)

Fostriecin inhibits protein phosphatases, which may alter the phosphorylation state of transcription factors regulating ZNF279.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor that can alter chromatin structure and potentially downregulate ZNF279 expression.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

SAHA is another histone deacetylase inhibitor that can change chromatin accessibility, possibly leading to reduced ZNF279 expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Sirolimus inhibits mTOR, which can lead to a broad decrease in protein synthesis, including potentially ZNF279.