ZIP3 Activators
Chemicals classified as ZIP3 activators encompass a diverse array of molecules that can indirectly influence the activity of ZIP3 by modulating cellular processes and signaling pathways related to metal ion homeostasis. ZIP3 functions as a transporter in the SLC39 (Solute carrier family 39) family, playing a crucial role in the absorption and cellular influx of zinc ions.
Some chemicals such as zinc sulfate, copper(II) sulfate, and iron(II) sulfate can potentially modulate the activity of ZIP3 by affecting cellular metal ion homeostasis. These metal salts provide a source of metal ions that compete with zinc for transport, stimulating the need for increased zinc uptake via ZIP3. Other molecules, namely cadmium chloride, lead(II) nitrate, and sodium arsenite, indirectly influence ZIP3 activity by disrupting cellular metal ion homeostasis, which prompts an increased need for zinc uptake via ZIP3. Finally, chemicals such as manganese(II) sulfate, sodium selenite, potassium dichromate, nickel(II) chloride, cobalt(II) chloride, and mercury(II) chloride can indirectly modulate the activity of ZIP3 by altering the balance of intracellular metal ions, thereby stimulating the need for increased zinc uptake via ZIP3. These chemicals, by altering the balance of metal ion homeostasis, can indirectly modulate the activity of ZIP3.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc sulfate is a source of zinc ions, which can indirectly stimulate ZIP3 by increasing intracellular zinc demand. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper(II) sulfate can indirectly influence ZIP3 by competing with zinc for transport, stimulating the need for increased zinc uptake via ZIP3. | ||||||
Ferrous Sulfate (Iron II Sulfate) Heptahydrate | 7782-63-0 | sc-211505 sc-211505A | 250 g 500 g | $73.00 $109.00 | ||
Iron(II) sulfate can indirectly affect ZIP3 by altering cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||
Manganese(II) sulfate monohydrate | 10034-96-5 | sc-203130 sc-203130A | 100 g 500 g | $41.00 $107.00 | ||
Manganese(II) sulfate can indirectly modulate ZIP3 activity by altering cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||
Lead (II) nitrate | 10099-74-8 | sc-211724 sc-211724A | 100 g 500 g | $40.00 $88.00 | ||
Lead(II) nitrate can indirectly modulate ZIP3 activity by disrupting cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Sodium arsenite can indirectly influence ZIP3 by disrupting cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||
Sodium selenite | 10102-18-8 | sc-253595 sc-253595B sc-253595C sc-253595A | 5 g 500 g 1 kg 100 g | $49.00 $183.00 $316.00 $98.00 | 3 | |
Sodium selenite can indirectly affect ZIP3 by altering cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||
Nickel(II) chloride | 7718-54-9 | sc-236169 sc-236169A | 100 g 500 g | $68.00 $188.00 | ||
Nickel(II) chloride can indirectly stimulate ZIP3 by competing with zinc for transport, prompting the need for increased zinc uptake via ZIP3. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $64.00 $176.00 | 7 | |
Cobalt(II) chloride can indirectly affect ZIP3 by altering cellular metal ion homeostasis, prompting an increased need for zinc uptake via ZIP3. | ||||||