ZDHHC18 Activators constitute a specialized category of chemical compounds that have garnered interest in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the ZDHHC18 gene, where ZDHHC18 stands for Zinc Finger, DHHC-Type Containing 18. This gene is a protein-coding element found in humans, and it belongs to a family of enzymes known as palmitoyltransferases. Palmitoyltransferases play a pivotal role in post-translational modification by catalyzing the addition of fatty acid groups, primarily palmitate, to specific protein targets. This modification, called palmitoylation, is essential for regulating protein localization, stability, and function within cells. ZDHHC18 Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the ZDHHC18 gene, ultimately leading to an increase in the activity of the associated palmitoyltransferase enzyme.
The mechanism of action of ZDHHC18 Activators generally involves their interaction with specific regulatory elements within the ZDHHC18 gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the ZDHHC18 enzyme. ZDHHC18 is believed to play a role in the palmitoylation of various protein targets, which can impact cellular processes, including membrane trafficking, protein-protein interactions, and signal transduction. As scientists delve deeper into the functions and potential implications of ZDHHC18 activation, the development and refinement of ZDHHC18 Activators offer the prospect of advancing our understanding of post-translational modifications, cellular biology, and the broader role of ZDHHC18 in cellular functionality and molecular pathways, potentially revealing novel aspects of protein regulation and cellular responses.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts ER-to-Golgi transport, which may lead to cellular stress and alter the expression of genes such as ZDHHC18. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling, which can influence cell growth and gene expression, potentially including ZDHHC18. |