Date published: 2025-10-12

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YTHD Antibodies

Santa Cruz Biotechnology features a diverse variety of YTHD Antibodies for specific detection and analysis of YTH domain-containing proteins. YTHD Antibodies are validated for multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). YTHD proteins play a crucial role in RNA metabolism and are involved in the recognition of N6-methyladenosine (m6A) modifications on RNA, which is essential for regulating gene expression and cellular processes. RNA modification patterns influence development, differentiation, and cellular responses to environmental stimuli. Research has shown that YTHD protein activity impacts various diseases, including cancer and neurological disorders. Understanding YTHD protein function and regulation provides valuable insights into RNA biology and disease mechanisms. Investigating m6A modifications and their readers continues to reveal new aspects of gene regulation. YTHD research using Santa Cruz Biotechnology monoclonal antibodies enables scientists to advance our understanding of RNA biology and its role in human health and disease.

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YTHD Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

YTHDF3 Antibody (F-2)

sc-377119mouse IgG2a κ85-119 (h)WB, IP, IF, IHC(P), ELISAm, r, h
23
(9)

YTHD CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ythdc1 CRISPR/Cas9 KO Plasmid (m)

sc-433061mGene KnockoutGFP0
(0)

Ythdc1 HDR Plasmid (m)

sc-433061-HDRmHomology Directed RepairPuromycin0
(0)

Ythdc1 Double Nickase Plasmid (m)

sc-433061-NICmGene KnockoutPuromycin0
(0)

Ythdc1 Double Nickase Plasmid (m2)

sc-433061-NIC-2mGene KnockoutPuromycin0
(0)

YTHDF1 CRISPR/Cas9 KO Plasmid (h)

sc-412379hGene KnockoutGFP0
(0)

YTHDF1 HDR Plasmid (h)

sc-412379-HDRhHomology Directed RepairPuromycin0
(0)

YTHDF1 Double Nickase Plasmid (h)

sc-412379-NIChGene KnockoutPuromycin0
(0)

YTHDF1 Double Nickase Plasmid (h2)

sc-412379-NIC-2hGene KnockoutPuromycin0
(0)

YTHDF1 CRISPR/Cas9 KO Plasmid (m)

sc-432834mGene KnockoutGFP0
(0)

YTHDF1 HDR Plasmid (m)

sc-432834-HDRmHomology Directed RepairPuromycin0
(0)

YTHDF1 Double Nickase Plasmid (m)

sc-432834-NICmGene KnockoutPuromycin0
(0)

YTHDF1 Double Nickase Plasmid (m2)

sc-432834-NIC-2mGene KnockoutPuromycin0
(0)

YTHDC2 CRISPR/Cas9 KO Plasmid (h2)

sc-407254-KO-2hGene KnockoutGFP0
(0)

YTHDC2 HDR Plasmid (h2)

sc-407254-HDR-2hHomology Directed RepairPuromycin0
(0)

YTHDC2 Double Nickase Plasmid (h)

sc-407254-NIChGene KnockoutPuromycin0
(0)

YTHDC2 Double Nickase Plasmid (h2)

sc-407254-NIC-2hGene KnockoutPuromycin0
(0)

YTHDC2 CRISPR/Cas9 KO Plasmid (m)

sc-433753mGene KnockoutGFP0
(0)

YTHDC2 HDR Plasmid (m)

sc-433753-HDRmHomology Directed RepairPuromycin0
(0)

YTHDC2 Double Nickase Plasmid (m)

sc-433753-NICmGene KnockoutPuromycin0
(0)

YTHDC2 Double Nickase Plasmid (m2)

sc-433753-NIC-2mGene KnockoutPuromycin0
(0)

YTHDF2 CRISPR/Cas9 KO Plasmid (h)

sc-416408hGene KnockoutGFP0
(0)

YTHDF2 HDR Plasmid (h)

sc-416408-HDRhHomology Directed RepairPuromycin0
(0)

YTHDF2 Double Nickase Plasmid (h)

sc-416408-NIChGene KnockoutPuromycin0
(0)

YTHDF2 Double Nickase Plasmid (h2)

sc-416408-NIC-2hGene KnockoutPuromycin0
(0)

YTHDF2 CRISPR/Cas9 KO Plasmid (m)

sc-431883mGene KnockoutGFP0
(0)

YTHDF2 HDR Plasmid (m)

sc-431883-HDRmHomology Directed RepairPuromycin0
(0)

YTHDF2 Double Nickase Plasmid (m)

sc-431883-NICmGene KnockoutPuromycin0
(0)

YTHDF2 Double Nickase Plasmid (m2)

sc-431883-NIC-2mGene KnockoutPuromycin0
(0)

YTHDF3 CRISPR/Cas9 KO Plasmid (h)

sc-404745hGene KnockoutGFP0
(0)

YTHDF3 HDR Plasmid (h)

sc-404745-HDRhHomology Directed RepairPuromycin0
(0)

YTHDF3 Double Nickase Plasmid (h)

sc-404745-NIChGene KnockoutPuromycin0
(0)

YTHDF3 Double Nickase Plasmid (h2)

sc-404745-NIC-2hGene KnockoutPuromycin0
(0)

YTHDF3 CRISPR/Cas9 KO Plasmid (m)

sc-432840mGene KnockoutGFP0
(0)

YTHDF3 HDR Plasmid (m)

sc-432840-HDRmHomology Directed RepairPuromycin0
(0)

YTHDF3 Double Nickase Plasmid (m)

sc-432840-NICmGene KnockoutPuromycin0
(0)

YTHDF3 Double Nickase Plasmid (m2)

sc-432840-NIC-2mGene KnockoutPuromycin0
(0)

YTHD CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ythdc1 CRISPR Activation Plasmid (m)

sc-433061-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Ythdc1 CRISPR Activation Plasmid (m2)

sc-433061-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Ythdc1 Lentiviral Activation Particles (m)

sc-433061-LACmGene ActivationPuro, Blast, Hygro0
(0)

Ythdc1 Lentiviral Activation Particles (m2)

sc-433061-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 CRISPR Activation Plasmid (h)

sc-412379-ACThGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 CRISPR Activation Plasmid (h2)

sc-412379-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 Lentiviral Activation Particles (h)

sc-412379-LAChGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 Lentiviral Activation Particles (h2)

sc-412379-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 CRISPR Activation Plasmid (m)

sc-432834-ACTmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 CRISPR Activation Plasmid (m2)

sc-432834-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 Lentiviral Activation Particles (m)

sc-432834-LACmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF1 Lentiviral Activation Particles (m2)

sc-432834-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 CRISPR Activation Plasmid (h)

sc-407254-ACThGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 CRISPR Activation Plasmid (h2)

sc-407254-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 Lentiviral Activation Particles (h)

sc-407254-LAChGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 Lentiviral Activation Particles (h2)

sc-407254-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 CRISPR Activation Plasmid (m)

sc-433753-ACTmGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 CRISPR Activation Plasmid (m2)

sc-433753-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 Lentiviral Activation Particles (m)

sc-433753-LACmGene ActivationPuro, Blast, Hygro0
(0)

YTHDC2 Lentiviral Activation Particles (m2)

sc-433753-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 CRISPR Activation Plasmid (h)

sc-416408-ACThGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 CRISPR Activation Plasmid (h2)

sc-416408-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 Lentiviral Activation Particles (h)

sc-416408-LAChGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 Lentiviral Activation Particles (h2)

sc-416408-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 CRISPR Activation Plasmid (m)

sc-431883-ACTmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 CRISPR Activation Plasmid (m2)

sc-431883-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 Lentiviral Activation Particles (m)

sc-431883-LACmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF2 Lentiviral Activation Particles (m2)

sc-431883-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 CRISPR Activation Plasmid (h)

sc-404745-ACThGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 CRISPR Activation Plasmid (h2)

sc-404745-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 Lentiviral Activation Particles (h)

sc-404745-LAChGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 Lentiviral Activation Particles (h2)

sc-404745-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 CRISPR Activation Plasmid (m)

sc-432840-ACTmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 CRISPR Activation Plasmid (m2)

sc-432840-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 Lentiviral Activation Particles (m)

sc-432840-LACmGene ActivationPuro, Blast, Hygro0
(0)

YTHDF3 Lentiviral Activation Particles (m2)

sc-432840-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

YTHD siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ythdc1 siRNA (m)

sc-155421mGene SilencingN/A0
(0)

Ythdc1 shRNA Plasmid (m)

sc-155421-SHmGene SilencingPuromycin0
(0)

Ythdc1 shRNA (m) Lentiviral Particles

sc-155421-VmGene SilencingPuromycin0
(0)

YTHDF1 siRNA (h)

sc-76945hGene SilencingN/A
2
(0)

YTHDF1 shRNA Plasmid (h)

sc-76945-SHhGene SilencingPuromycin
2
(0)

YTHDF1 shRNA (h) Lentiviral Particles

sc-76945-VhGene SilencingPuromycin
2
(0)

YTHDF1 siRNA (m)

sc-155423mGene SilencingN/A
2
(0)

YTHDF1 shRNA Plasmid (m)

sc-155423-SHmGene SilencingPuromycin
2
(0)

YTHDF1 shRNA (m) Lentiviral Particles

sc-155423-VmGene SilencingPuromycin
2
(0)

YTHDC2 siRNA (h)

sc-91804hGene SilencingN/A0
(0)

YTHDC2 shRNA Plasmid (h)

sc-91804-SHhGene SilencingPuromycin0
(0)

YTHDC2 shRNA (h) Lentiviral Particles

sc-91804-VhGene SilencingPuromycin0
(0)

YTHDC2 siRNA (m)

sc-155422mGene SilencingN/A0
(0)

YTHDC2 shRNA Plasmid (m)

sc-155422-SHmGene SilencingPuromycin0
(0)

YTHDC2 shRNA (m) Lentiviral Particles

sc-155422-VmGene SilencingPuromycin0
(0)

YTHDF2 siRNA (h)

sc-78661hGene SilencingN/A
4
(0)

YTHDF2 shRNA Plasmid (h)

sc-78661-SHhGene SilencingPuromycin
4
(0)

YTHDF2 shRNA (h) Lentiviral Particles

sc-78661-VhGene SilencingPuromycin
4
(0)

YTHDF2 siRNA (m)

sc-155424mGene SilencingN/A
2
(0)

YTHDF2 shRNA Plasmid (m)

sc-155424-SHmGene SilencingPuromycin
2
(0)

YTHDF2 shRNA (m) Lentiviral Particles

sc-155424-VmGene SilencingPuromycin
2
(0)

YTHDF3 siRNA (h)

sc-77724hGene SilencingN/A
1
(0)

YTHDF3 shRNA Plasmid (h)

sc-77724-SHhGene SilencingPuromycin
1
(0)

YTHDF3 shRNA (h) Lentiviral Particles

sc-77724-VhGene SilencingPuromycin
1
(0)